Aims: To estimate the effect of plantar-flexion on the wave amplitude of involuntary detrusor contraction and the severity of urinary urgency during filling cystometry in patients with detrusor overactivity (DO).
Methods: Twenty-two consecutive patients with DO were enrolled. During urodynamics, the mean peak detrusor pressures of each contraction were documented and compared. At the beginning of the 2nd or 3rd wave, patients were asked to perform continuous plantar-flexion by pushing their tiptoes against the floor. Following each wave, patients were asked to grade the severity of the urgency by a visual analogue scale (VAS).
Results: The mean peak detrusor pressure without plantar-flexion was 58 cmH2 O (95% CI: 46.3-69.7) compared to 31 cmH2 O (95% CI: 23.1-38.9) with plantar-flexion (P < 0.001). All patients reported a reduced degree of urgency during plantar-flexion reflected in a significant reduction in mean VAS score from 9.3 (95% CI: 9-9.5) to 4.7 (95% CI: 3.9-5.4; P < 0.0001).
Conclusions: Self-performed plantar-flexion maneuver might reduce the severity of urinary urgency and the magnitude of overactive detrusor contractions, which may have a role in the conservative therapy of detrusor overactivity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/nau.22493 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[The improvement effects of TAVR on cardiac electrical remodeling of patients with severe aortic stenosis].
Zhonghua Xin Xue Guan Bing Za Zhi
January 2025
Cardiology Department, Second Affiliated Hospital of Dalian Medical University, Dalian116021, China.
To assess the effectiveness of transcatheter aortic valve replacement (TAVR) on electrocardiographic remodeling in patients with severe aortic stenosis (AS), and identify its influencing factors. A cohort study was conducted on patients with a confirmed diagnosis of severe AS who successfully underwent TAVR at the Second Affiliated Hospital of Dalian Medical University between June 2018 and March 2023. Data, including standard 15-lead electrocardiograms and echocardiograms, were collected before the operation, 1 week after the operation, and 3 months after the operation.
View Article and Find Full Text PDFBroadband Long Wavelength Light Promotes Myopic Eye Growth and Alters Retinal Responses to Light Offset in Chick.
Invest Ophthalmol Vis Sci
January 2025
School of Psychology and Public Health, La Trobe University, Melbourne, Australia.
Purpose: Prolonged exposure to broadband light with a short-wavelength (blue) or long-wavelength (orange/red) bias is known to impact eye growth and refraction, but the mechanisms underlying this response are unknown. Thus, the present study investigated the effects of broadband blue and orange lights with well-differentiated spectrums on refractive development and global flash electroretinography (gfERG) measures of retinal function in the chick myopia model.
Methods: Chicks were raised for 4 days with monocular negative lenses, or no lens, under blue, orange, or white light.
The fractional nonlinear Schrödinger equation: Soliton turbulence, modulation instability, and extreme rogue waves.
Chaos
January 2025
KLMM, Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190, China.
In this paper, we undertake a systematic exploration of soliton turbulent phenomena and the emergence of extreme rogue waves within the framework of the one-dimensional fractional nonlinear Schrödinger (FNLS) equation, which appears in many fields, such as nonlinear optics, Bose-Einstein condensates, plasma physics, etc. By initiating simulations with a plane wave modulated by small noise, we scrutinized the universal regimes of non-stationary turbulence through various statistical indices. Our analysis elucidates a marked increase in the probability of rogue wave occurrences as the system evolves within a certain range of Lévy index α, which can be ascribed to the broadened modulation instability bandwidth.
View Article and Find Full Text PDFPhytochlorin-Based Sonosensitizers Combined with Free-Field Ultrasound for Immune-Sonodynamic Cancer Therapy.
Adv Mater
January 2025
State Key Laboratory of Fine Chemicals, Department of Pharmacy, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China.
Phytochlorins, a class of plant-derived tetrapyrroles, show great potential as sonosensitizers in sonodynamic therapy (SDT). The development of new phytochlorin-based sonosensitizers has significantly improved SDT, yet the absence of specialized sonodynamic systems limits their clinical translation. Herein, a dedicated ultrasound system along with a detailed step-by-step sonodynamic process from in vitro to in vivo is developed to activate phytochlorin-based sonosensitizers.
View Article and Find Full Text PDFAttenuation of progressive surface gravity waves by floating spheres.
Sci Rep
January 2025
Faculty of Civil Engineering and Geosciences, Delft University of Technology, 2628 CD, Delft, The Netherlands.
Laboratory experiments were performed to investigate the attenuation of progressive deep-water waves by a mono-layer of loose- and close-packed floating spheres. We measured the decay distance of waves having different incident wave frequency and steepness. The attenuation of waves was strong if the surface concentration of particles was close-packed, with the decay distance being shorter for incident waves with higher frequency and steepness.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!