The synthesis, structure elucidation and the complete (1)H and (13)C signal assignment of a series of dioxolane derivatives of 20-hydroxyecdysone, synthesized as novel modulators of multidrug resistance, are presented. The structures and NMR signal assignment were established by comprehensive one-dimensional and two-dimensional NMR spectroscopy supported by mass spectrometry.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/mrc.4015 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
NF-B Inhibitory Activity of the Di-Hydroxy Derivative of Piperlongumine (PL-18).
J Immunol Res
January 2025
Department of Microbiology, Immunology and Genetics Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84105, Israel.
Inflammation is a critical response of the immune system to infection or injury, serving to repair and restore tissue homeostasis. While acute inflammation generally protects against harmful stimuli, prolonged and chronic inflammation have detrimental effects and disrupts tissue homeostasis. Due to the complex and multifactorial etiology of chronic inflammation, effective treatment remains elusive.
View Article and Find Full Text PDFIn situ Polymerized Solid-State Electrolyte Enabling Inorganic-Organic Dual-Layered SEI Film for Stable Lithium Metal Batteries.
Small
January 2025
School of Environment and Energy, Guangdong Provincial Key Laboratory of Advanced Energy Storage Materials, South China University of Technology, Guangzhou, 510006, P. R. China.
In situ polymerization of cyclic ethers is a promising strategy to construct solid-state lithium (Li) metal batteries with high energy density and safety. However, their practical applications are plagued by the unsatisfactory electrochemical properties of polymer electrolytes and the unstable solid electrolyte interphase (SEI). Herein, organic perfluorodecanoic acid (PFDA) is proposed as a new initiator to polymerize 1,3-dioxolane electrolyte (PDOL), which enables the as-obtained PDOL electrolyte to deliver greatly enhanced ionic conductivity and broadened electrochemical window.
View Article and Find Full Text PDFTuning steric hindrance of cyclic ether electrolytes enables high-voltage lithium metal batteries.
J Colloid Interface Sci
December 2024
School of Materials Science and Engineering, Key Laboratory of Green Fabrication and Surface Technology of Advanced Metal Materials of Ministry of Education, Anhui University of Technology, Maanshan 243002, China; Key Laboratory of Efficient Conversion and Solid-state Storage of Hydrogen & Electricity of Anhui Province, Maanshan 243002, China. Electronic address:
Ether-based electrolytes are known for their high stability with lithium metal anodes (LMAs), but they often exhibit poor high-voltage stability. Structural optimization of ether-based solvent molecules has been proven to effectively broaden the electrochemical window of these electrolytes, yet the optimization rules within cyclic ethers remain unclear. Herein, we investigate the impact of methyl substitution positions on the molecular properties of 1,3-dioxolane (DOL), a commonly used cyclic ether.
View Article and Find Full Text PDFCharacterization and analysis of the bioactivity of the Piper rivinoides Kunth essential oil and its components myristicin and elemicin, against opportunistic fungal pathogens.
Microb Pathog
February 2025
Universidade Regional Do Cariri - URCA, Rua Cel. Antônio Luiz, 1161 - Pimenta, Crato, CE, Brazil.
Candidiasis is an infectious disease caused by some fungi of the genus Candida. In Brazil, the incidence rate is higher than in European countries and the United States, and health problems occur mainly due to the virulence factors of the fungi, which have made treatment with commercial drugs difficult. Considering the context, plants rich in phenolic compounds, such as those of the genus Piper, have been studied due to their antimicrobial properties.
View Article and Find Full Text PDFToxicological Analysis of the Arylnaphthalene Lignan Justicidin B Using a Model.
Molecules
November 2024
Department of Biotechnologies and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.
The screening of plant-derived compounds with anti-cancer properties is a promising strategy to meet the growing need for new, safe and effective anti-cancer drugs. Justicidin B is a plants secondary metabolite that displays anti-cancer properties in several tumor cells. Therefore, it represents a good candidate.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!