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http://dx.doi.org/10.1016/j.fertnstert.2013.08.053 | DOI Listing |
J Insect Sci
July 2024
Faculty of Agricultural and Nutritional Sciences, Institute of Animal Nutrition and Feed Science, Christian-Albrechts-Universität zu Kiel, Schleswig-Holstein, Germany.
The study aims to assess the impact of oven-drying and decontamination on crude protein concentration and in vitro crude protein digestibility of yellow mealworms. Two kilograms of 12-wk-old mealworm larvae were subjected to freezing prior to the drying process. Approximately 1.
View Article and Find Full Text PDFInt J Pharm Compd
June 2023
Global Alliance for TB Drug Development (TB Alliance), New York, New York.
Tablet formulations fail to meet the needs of patients unable to swallow tablets such as pediatric, elderly, and patients that must receive medications via feeding tubes. Our objective was to develop and test a new, simple device (XTEMP-R) and the methodology for converting tablets into a homogeneous suspension for medication administration. We developed a new device comprised of a flexible receptacle, a tight-fitting cap, and a suction cup bottom to convert tablets into liquid preparations.
View Article and Find Full Text PDFJ Am Vet Med Assoc
August 2023
1Department of Avian and Exotics, Red Bank Veterinary Hospital, Tinton Falls, NJ.
Objective: To evaluate the sterility of citrate phosphate dextrose adenine (CPDA-1) anticoagulant when sampled from blood collection bags in a multi-dose manner.
Sample: 10 pre-filled CPDA-1 blood collection bags; 46 bacterial and 28 fungal culture result reports.
Procedures: 10 CPDA-1 blood collection bags were split into 2 equal groups and stored at either room temperature (24 °C) or refrigerator temperature (5 °C) for 30 days.
Comput Biol Med
February 2023
Advanced Computation and Data Sciences Division, CSIR- North East Institute of Science and Technology, Jorhat, 785006, Assam, India; Polymers and Functional Materials Division, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, Uttar Pradesh, India. Electronic address:
One of the major challenges in drug development is having acceptable levels of efficacy and safety throughout all the phases of clinical trials followed by the successful launch in the market. While there are many factors such as molecular properties, toxicity parameters, mechanism of action at the target site, etc. that regulates the therapeutic action of a compound, a holistic approach directed towards data-driven studies will invariably strengthen the predictive toxicological sciences.
View Article and Find Full Text PDFBMC Med Res Methodol
May 2022
Department of Research in Biomedicine and Health, School of Medicine, University of Split, Šoltanska 2, 21000, Split, Croatia.
Background: To assess registration completeness and safety data of trials on human genome editing (HGE) reported in primary registries and published in journals, as HGE has safety and ethical problems, including the risk of undesirable and unpredictable outcomes. Registration transparency has not been evaluated for clinical trials using these novel and revolutionary techniques in human participants.
Methods: Observational study of trials involving engineered site-specific nucleases and long-term follow-up observations, identified from the WHO ICTRP HGE Registry in November 2020 and two comprehensive reviews published in the same year.
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