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The paradoxical activity of BRAF inhibitors: potential use in wound healing.
Arch Dermatol Res
January 2025
Department of Translational & Clinical Research, School of Chemical and Life Sciences, Jamia Hamdard, Hamdard Nagar, New Delhi, 110062, India.
The area of wound healing presents a promising field of interest for clinicians as well as the scientific community. A major concern for physicians is the rising number of elderly people suffering from diabetes, leprosy, tuberculosis and the associated chronic wounds. While traditional therapies target basic wound care, innovative strategies that accelerate wound healing are needed.
View Article and Find Full Text PDFA rapid and simple MALDI-TOF MS lipid profiling method for differentiating from .
J Clin Microbiol
January 2025
Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Higashimurayama, Tokyo, Japan.
, a slow-growing nontuberculous mycobacterium, causes Buruli ulcer, a neglected tropical disease. Distinguishing from related species, including , poses challenges with respect to making accurate identifications. In this study, we developed a rapid and simple identification method based on mycobacterial lipid profiles and used matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) to analyze the lipid profiles of ( = 35) and ( = 19) isolates.
View Article and Find Full Text PDFA Case of Lepromatous Leprosy Presenting With Multiple Morphologies in Philadelphia.
Cureus
December 2024
Dermatology, Temple University Hospital, Philadelphia, USA.
Leprosy is an uncommon chronic mycobacterial infection in the United States caused by . There are two major forms of the infection, lepromatous leprosy and tuberculoid leprosy, with borderline forms of each. Leprosy is even more uncommon in the Northeastern United States and can present with various symptoms and skin findings, including erythematous or hypopigmented patches or plaques with accompanying hypoesthesia or anesthesia, anhidrosis, or alopecia.
View Article and Find Full Text PDFEmergence of Carbapenem-Resistant Harboring Isolated from River Water in Ghana.
Antibiotics (Basel)
January 2025
Department of Molecular Microbiology and Immunology, Institute of Science Tokyo, Tokyo 113-8510, Japan.
, known for carrying the gene and linked to various diseases, is widely distributed. However, its prevalence in Ghana is unknown, mainly due to misidentification or inadequate research. In this study, for the first time, we characterized from Densu river water in Ghana.
View Article and Find Full Text PDFCharacterization of the Population of Ovarian Preantral Follicles in Juvenile Six-Banded Armadillos Infected or Not by .
Vet Sci
January 2025
Laboratory on Animal Germplasm Conservation, Federal University of Semiarid Region-UFERSA, Mossoró 59600, Brazil.
The objective of this study was to characterize and estimate the population of ovarian preantral follicles in juvenile six-banded armadillos. Pairs of ovaries from five armadillos were collected during a routine epidemiological survey of leprosis (three healthy and two infected females). Ovaries weighed approximately 0.
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