Four levels of wavelength-selective uncaging for oligonucleotides.

Org Lett

Institute for Organic Chemistry and Chemical Biology, Buchmann Institute for Molecular Life Sciences, Goethe-University Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt, Germany.

Published: November 2013

In this study the new nucleobase-caged nucleotides dT(NpHP) and dT(DEACM) are introduced. Together with two other caging groups (NDBF and NPP) this results in four layers of wavelength-selective uncaging for oligonucleotides, sequentially going from 505 to 440 nm, 365 nm, and finally to 313 nm for the photolysis reaction.

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Source
http://dx.doi.org/10.1021/ol402657jDOI Listing

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