Tinnitus is the perception of sound in the ears or in the head where no external source is present. Sound therapy is one of the most effective techniques for tinnitus treatment that have been proposed. In order to investigate mechanisms of tinnitus generation and the clinical effects of sound therapy, we have proposed conceptual and computational models with plasticity using a neural oscillator or a neuronal network model. In the present paper, we propose a neuronal network model with simplified tonotopicity of the auditory system as more detailed structure. In this model an integrate-and-fire neuron model is employed and homeostatic plasticity is incorporated. The computer simulation results show that the present model can show the generation of oscillation and its cessation by external input. It suggests that the present framework is promising as a modeling for the tinnitus generation and the effects of sound therapy.
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http://dx.doi.org/10.1109/EMBC.2013.6610911 | DOI Listing |
J Acoust Soc Am
January 2025
Department of Apparel and Space Design, Kyoto Women's University, Kyoto, Kyoto 605-8501, Japan.
Ever since de Saussure [Course in General Lingustics (Columbia University Press, 1916)], theorists of language have assumed that the relation between form and meaning of words is arbitrary. However, recently, a body of empirical research has established that language is embodied and contains iconicity. Sound symbolism, an intrinsic link language users perceive between word sound and properties of referents, is a representative example of iconicity in language and has offered profound insights into theories of language pertaining to language processing, language acquisition, and evolution.
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January 2025
Collaborative Antwerp Psychiatric Research Institute (CAPRI), University of Antwerp, Antwerp, Belgium.
Background: Recent years show an exponential increased interest ("renaissance") in the use of psychedelics for the treatment of mental disorders and broader. Some of these treatments, such as psilocybin for depression, are in the process of formal regulation by regulatory bodies in the US (FDA) and Europe (EMA), and as such on the brink of real-world implementation. In the slipstream of these developments increasing commercial initiatives are taking shape.
View Article and Find Full Text PDFCureus
December 2024
Microbiology, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, BRA.
During the COVID-19 pandemic, masks were widely promoted and mandated as a key measure to help reduce the transmission of SARS-CoV-2. These policies were primarily informed by laboratory evidence demonstrating the effectiveness of particle filtration, alongside observational studies. While several meta-analyses have indicated that masks may contribute to reducing viral transmission, many of these analyses rely heavily on observational data.
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December 2024
Ophthalmology Examination Department, Sakoh Eye Clinic, Kawasaki, JPN.
We present three cases where traditional occlusion therapy with an eye patch proved ineffective for treating amblyopia associated with fusion maldevelopment nystagmus. In these cases, we transitioned to dichoptic therapy using the Occlu-pad, achieving successful outcomes. Eye patch occlusion of the sound eye consistently exacerbated nystagmus, whereas dichoptic treatment did not.
View Article and Find Full Text PDFEur J Case Rep Intern Med
December 2024
Internal Medicine, Holy Family Hospital, Rawalpindi, Pakistan.
Background: Andersen-Tawil syndrome (ATS) is a rare autosomal dominant disorder caused by variants in the gene. It is associated with periodic paralysis, dysmorphic features and cardiac arrhythmias. The syndrome exhibits incomplete penetrance, leading to a broad spectrum of clinical manifestations, making diagnosis challenging.
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