Adventitious lung sounds (ALS) as crackles and wheezes are present in different lung alterations and their automated characterization and recognition have become relevant. In fact, recently their 2D spatial distribution (SD) imaging has been proposed to help diagnose of pulmonary diseases. In this work, independent component analysis (ICA) by infomax was used to find crackles sources and from them to apply a time variant autoregressive model (TVAR) to count and imaging the ALS. The proposed methodology was assessed on multichannel LS recordings by embedding simulated fine crackles with known SD in recorded normal breathing sounds. Afterwards, the adventitious image of two patients with fibrosis and emphysema were obtained and contrasted with the classical pulmonary auscultation provided by a pneumologist. The results showed that combining ICA and TVAR leads to a robust methodology to imaging ALS.
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http://dx.doi.org/10.1109/EMBC.2013.6609760 | DOI Listing |
Minerva Pediatr (Torino)
December 2024
CINTESIS@RISE, MEDCIDS, Faculty of Medicine, University of Porto, Porto, Portugal -
Background: Lung auscultation using a smartphone built-in microphone is promising for home monitoring of pediatric respiratory diseases. Our aim was to compare respiratory sounds recorded by a smartphone and a digital stethoscope by assessing the proportion of quality recordings and adventitious sounds detected by each device.
Methods: A comparative early feasibility study with children from a public school in Northern Portugal was conducted.
Biomolecules
October 2024
School of Biological and Chemical Engineering, NingboTech University, Ningbo 315100, China.
(1) Background: Methyl jasmonate-treated adventitious root extract (MeJA-DMARE), enriched with phenolics, has enhanced bioactivities. However, phenolics possess low stability and bioavailability. Substantial evidence indicates that plant extract-phospholipid complex assemblies, known as phytosomes, represent an innovative drug delivery system.
View Article and Find Full Text PDFBioengineering (Basel)
June 2024
Department of Electrical Electronic and Computer Engineering, University of Ulsan, Ulsan 44610, Republic of Korea.
Respiratory diseases are among the leading causes of death, with many individuals in a population frequently affected by various types of pulmonary disorders. Early diagnosis and patient monitoring (traditionally involving lung auscultation) are essential for the effective management of respiratory diseases. However, the interpretation of lung sounds is a subjective and labor-intensive process that demands considerable medical expertise, and there is a good chance of misclassification.
View Article and Find Full Text PDFBiomolecules
June 2024
School of Biological and Chemical Engineering, NingboTech University, Ningbo 315100, China.
(1) Background: Phytochemicals are crucial antioxidants that play a significant role in preventing cancer. (2) Methods: We explored the use of methyl jasmonate (MeJA) in the in vitro cultivation of adventitious roots (DMAR) and evaluated its impact on secondary metabolite production in DMAR, optimizing concentration and exposure time for cost-effectiveness. We also assessed its anti-inflammatory and anti-lung cancer activities and related gene expression levels.
View Article and Find Full Text PDFPneumonia (Nathan)
June 2024
1st Intensive Care Unit, "G. Papanikolaou" General Hospital, Exochi Thessalonikis, 57010, Greece.
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