NaH mediated isomerisation-allylation reaction of 1,3-substituted propenols.

Org Biomol Chem

School of Chemistry and Chemical Engineering, Queen's University Belfast, Belfast, Northern Ireland, UK.

Published: November 2013

A base mediated isomerisation-allylation protocol of 1,3-disubstituted propenols has been established. The use of diaryl and aryl-silyl substrates is reported alongside the use of substituted allyl bromides. Mechanistic experiments have also been conducted to elucidate the reaction pathway.

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Source
http://dx.doi.org/10.1039/c3ob41857jDOI Listing

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