"Clickable" LNA/DNA probes for fluorescence sensing of nucleic acids and autoimmune antibodies.

Chem Commun (Camb)

Nucleic Acid Center, Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, DK-5230 Odense M, Denmark.

Published: November 2013

Herein we describe fluorescent oligonucleotides prepared by click chemistry between novel alkyne-modified locked nucleic acid (LNA) strands and a series of fluorescent azides for homogeneous (all-in-solution) detection of nucleic acids and autoimmune antibodies.

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Source
http://dx.doi.org/10.1039/c3cc45507fDOI Listing

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