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http://dx.doi.org/10.5811/westjem.2013.3.16184 | DOI Listing |
Int J Drug Policy
January 2025
Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, 1812 Ashland Avenue, 3rd Floor, Baltimore, MD 21205, USA.
Background: While the unregulated drug market has seen dramatic increases in fentanyl adulteration in the past decade, other adulterants have impacted the recent volatility of the drug supply. There has been recent documentation related to the presence of wound-associated substances; however, there is a lack of data showing the prevalence of these substances across unregulated drug market samples over time. The aim of this paper is to examine known and potential wound-associated agents' (xylazine, levamisole, medetomidine) prevalence in Maryland's unregulated drug supply.
View Article and Find Full Text PDFAnal Methods
July 2024
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt.
A simple and sensitive fluorescent probe has been developed and optimized to detect the non-intentional administration of levamisole (LVM). LVM is used as an anthelmintic therapy in cows, and hence, its residues appear in the drained milk until 60 hours after administering the drug. Meanwhile, levamisole is known to be an adulterant to cocaine and could be detected in addicts' plasma samples.
View Article and Find Full Text PDFDermatologie (Heidelb)
August 2024
Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Essen, Hufelandstr. 55, 45147, Essen, Deutschland.
J Pharm Biomed Anal
September 2024
Superintendência da Polícia Federal, Porto Alegre, RS, Brazil; Instituto Nacional de Ciência e Tecnologia Forense (INCT Forense), Brazil.
Street cocaine is often mixed with various substances that intensify its harmful effects. This paper proposes a framework to identify attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) intervals that best predict the concentration of adulterants in cocaine samples. Wavelengths are ranked according to their relevance through ReliefF and mRMR feature selection approaches, and an iterative process removes less relevant wavelengths based on the ranking suggested by each approach.
View Article and Find Full Text PDFDrug Alcohol Rev
May 2024
Get Your Drugs Tested, Vancouver, Canada.
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