We describe an augmented topological map as an alternative for the proposed bicoded map. Inverting causality, the special nature of the vertical dimension is then no longer fixed a priori and the cause of specific navigation behavior, but a consequence of the combination of the specific geometry of the experimental environment and the motor capabilities of the experimental animals.
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http://dx.doi.org/10.1017/S0140525X13000502 | DOI Listing |
BMC Bioinformatics
January 2025
School of Information and Artificial Intelligence, Anhui Agricultural University, Changjiang West Road, Hefei, 230036, Anhui, China.
Drug-target interactions (DTIs) are pivotal in drug discovery and development, and their accurate identification can significantly expedite the process. Numerous DTI prediction methods have emerged, yet many fail to fully harness the feature information of drugs and targets or address the issue of feature redundancy. We aim to refine DTI prediction accuracy by eliminating redundant features and capitalizing on the node topological structure to enhance feature extraction.
View Article and Find Full Text PDFAdv Mater
December 2024
The Soft2D Lab, State Key Laboratory of Metal Matrix Composites, Shanghai Key Laboratory of Electrical Insulation and Thermal Ageing, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
The electrochemical conversion of carbon dioxide (CO) into hydrocarbon products emerges as a pivotal sustainable strategy for carbon utilization. Cu-based catalysts are currently prioritized as the most effective means for this process, yet it remains a long-term goal to achieve high product selectivity at elevated current densities. This study delved into exploring the influence of a topological poly(2-aminoazulene) with a substantial dipole moment on modulating the Cu surface dipole field to augment the catalytic activity involved in CO reduction.
View Article and Find Full Text PDFComput Biol Med
January 2025
Institute of Medical Information, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS&PUMC), Beijing, 100020, China. Electronic address:
The perfect optical vortex beam (POVB), renowned for its consistent beam radius across various orbital angular momentum (OAM) modes, excels in applications such as optical tweezers and communication. In our study, we achieved a significant milestone by creating a multi-ring perfect optical vortex beam (MR-POVB) through the superposition of multiple POVBs. This beam design maintains the inherent advantages of POVB while enabling multidimensional encoding via adjustable topological charges, radii, and intensities of each ring, thereby augmenting the free-space optical communication's channel capacity.
View Article and Find Full Text PDFComput Biol Med
January 2025
The Key Lab of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, 400044, Chongqing, China. Electronic address:
The quantitative analysis of Programmed death-ligand 1 (PD-L1) via Immunohistochemical (IHC) plays a crucial role in guiding immunotherapy. However, IHC faces challenges, including high costs, time consumption and result variability. Conversely, Hematoxylin-Eosin (H&E) staining offers cost-effectiveness, speed, and stable results.
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