N-(4-Acetyl-3-methyl-1-phenyl-1H-pyrazol-5-yl)-N-methyl-2-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)benzamide.

Acta Crystallogr Sect E Struct Rep Online

Department of Pharmaceutical Sciences, University of Milano, via L. Mangiagalli, 25, 20133-Milano, Italy.

Published: October 2013

In the title compound, C29H25N5O3, the dihedral angle between the benzene ring and the pendant quinazoline ring system (r.m.s. deviation = 0.036Å) is 87.60 (17)°. The equivalent angle between the pyrazole ring and the phenyl group is 70.0 (2)°. The dihedral angle between the benzene and pyrazole rings is 30.7 (2)° and overall, the mol-ecular conformation approximates to a Z shape. A short intra-molecular C-H⋯O contact occurs. In the crystal, the mol-ecules are linked by Cπ-H⋯O-type hydrogen bonds and aromatic π-π stacking inter-actions [centroid-centroid distance = 3.860 (3) Å], generating a three-dimensional network.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790439PMC
http://dx.doi.org/10.1107/S1600536813025683DOI Listing

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