Purpose: To investigate the use of a software-based pre-treatment QA system for VMAT, which incorporates realistic linac motion during delivery.
Methods: A beam model was produced using the GATE platform for GEANT4 Monte Carlo dose calculations. Initially validated against static measurements, the model was then integrated with a VMAT delivery emulator, which reads plan files and generates a set of dynamic delivery instructions analogous to the linac control system. Monte Carlo simulations were compared to measurements on dosimetric phantoms for prostate and head and neck VMAT plans. Comparisons were made between calculations using fixed control points, and simulations of continuous motion utilising the emulator. For routine use, the model was incorporated into an automated pre-treatment QA system.
Results: The model showed better agreement with measurements when incorporating linac motion: mean gamma pass (Γ<1) over 5 prostate plans was 100.0% at 3%/3mm and 97.4% at 2%/2mm when compared to measurement. For the head and neck plans, delivered to the anatomical phantom, gamma passes were 99.4% at 4%/4mm and 94.94% at 3%/3mm. For example simulations within patient CT data, gamma passes were observed which are within our centre's tolerance for pre-treatment QA.
Conclusions: Through comparison to phantom measurements, it was found that the incorporation of a realistic linac motion improves the accuracy of the model compared to the simulation of fixed control points. The ability to accurately calculate dose as a second check of the planning system, and determine realistic delivery characteristics, may allow for the reduction of machine-based pre-treatment plan QA for VMAT.
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http://dx.doi.org/10.1016/j.radonc.2013.08.046 | DOI Listing |
Strahlenther Onkol
January 2025
Department of Radiation Oncology, Radboud university medical center, Nijmegen, The Netherlands.
Purpose: This study focused on reducing the margin for prostate cancer treatment using magnetic resonance imaging-guided radiotherapy by investigating the intrafractional motion of the prostate and different motion-mitigation strategies.
Methods: We retrospectively analyzed intrafractional prostate motion in 77 patients with low- to intermediate-risk prostate cancer treated with five fractions of 7.25 Gy on a 1.
Clin Transl Radiat Oncol
March 2025
Department of Radiation Oncology, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.
Purpose: To use imaging data from stereotactic MR-guided online adaptive radiotherapy (SMART) of ultracentral lung tumors (ULT) for development of a safe non-adaptive approach towards stereotactic body radiotherapy (SBRT) of ULT.
Patients And Methods: Analysis is based on 19 patients with ULT who received SMART (10 × 5.0-5.
J Appl Clin Med Phys
January 2025
Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands.
Introduction: This paper describes a method to improve gantry-dependent beam steering for Elekta traveling wave linear accelerators by applying the measured and filtered beam servo corrections to the existing lookup table (LUT). Beam steering has a direct influence on the treatment accuracy by affecting the beam symmetry and position. The presented method provides an improved LUT with respect to the default Elekta method to reduce treatment delivery interruptions.
View Article and Find Full Text PDFJ Pers Med
November 2024
Department of Radiation Oncology, Miulli General Regional Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.
. Adult medulloblastoma (AMB) patients should receive postoperative craniospinal irradiation (CSI) as a standard treatment. Volumetric intensity-modulated arc therapy (VMAT) is a promising method for CSI.
View Article and Find Full Text PDFMed Phys
December 2024
Department of Physics, The Verspeeten Family Cancer Centre, London, Ontario, Canada.
Background: Stereotactic arrythmia radioablation (STAR) is a noninvasive technique to treat ventricular tachycardia (VT). Management of cardiorespiratory motion plays an essential role in VT-STAR treatments to improve treatment outcomes by reducing positional uncertainties and increasing dose conformality. Use of an electrocardiogram (ECG) signal, acquired in real-time, as a surrogate to gate the beam has the potential to fulfil that intent.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!