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Treatment Patterns and Healthcare Costs Among Patients with Stroke and Spasticity: A 2-Year Longitudinal Study.
Neurol Ther
December 2024
Ipsen, 1 Main Street, Suite 700, Cambridge, MA, 02142, USA.
Introduction: Post-stroke spasticity (PSS) occurs in ~25-43% of patients between 2 weeks and 3 months following a stroke. This retrospective claims study examined the occurrence of spasticity, treatment patterns, healthcare resource utilization, and healthcare costs among patients who experienced a stroke over a 2-year period.
Methods: Analyses were conducted using healthcare claims from the IQVIA PharMetrics Plus database of commercially/self-insured members from 2015 to 2021.
Comparative Phylogenetic Analysis and Protein Prediction Reveal the Taxonomy and Diverse Distribution of Virulence Factors in Foodborne Strains.
Evol Bioinform Online
November 2024
School of Yunkang Medicine and Health, Nanfang College, Guangzhou, Guangdong, China.
Background: and , 2 major foodborne pathogenic fusobacteria, have a variety of virulent protein types with nervous and enterotoxic pathogenic potential, respectively.
Objective: The relationship between the molecular evolution of the 2 genomes and virulence proteins was studied via a bioinformatics prediction method. The genetic stability, main features of gene coding and structural characteristics of virulence proteins were compared and analyzed to reveal the phylogenetic characteristics, diversity, and distribution of virulence factors of foodborne strains.
Real-World Use of Intradetrusor Botulinum Toxin Injections: A Population-Based Study from France.
Toxins (Basel)
October 2024
Neuro-Uro-Andrology Department, Raymond Poincaré Hospital, 92380 Garches, France.
In recent decades, intradetrusor injections of botulinum toxin A (BoNT-A) have been widely applied to treat incontinence in both idiopathic overactive bladder (iOAB) and neurogenic detrusor overactivity incontinence (NDOI). This analysis, based on the French National Hospital Discharge Database (PMSI), aims to describe real-world trends in intradetrusor BoNT-A use between 2014 and 2022. Among 32,864 patients who received at least one intradetrusor BoNT-A injection, 18,320 (55.
View Article and Find Full Text PDFCurriculum guide for teaching house officers and faculty: applying procedure codes effectively using chemical denervation as a model.
Front Med (Lausanne)
September 2024
Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, United States.
Introduction: The healthcare system in the United States relies heavily on physician-and house officer-driven initiation of billing and coding for collection of hospital payments and professional fees. Under the umbrella of practice management is the ever-changing and suboptimally taught concept of procedural billing and coding to house officers and faculty. Clinical providers and practitioners initiate billing and coding for performed services based on the procedural visit encounter, supported by the appropriate documentation.
View Article and Find Full Text PDFLiving With Spasticity During the COVID-19 Pandemic: A Qualitative Study of Patient, Carer and Physician Experiences.
Health Expect
October 2024
School of Psychology, University of Kent, Canterbury, UK.
Background: Approximately 4.4 million people in England (8% of the total population) are living with a long-term neurological condition. Within this group of vulnerable individuals, there will be individuals living with severe spasticity that requires regular outpatient treatment with botulinum toxin injection.
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