Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665116 | PMC |
| http://dx.doi.org/10.1016/j.exphem.2013.09.008 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
MicroRNAs as Epigenetic Regulators of Obesity.
Adv Exp Med Biol
September 2024
Faculty of Medicine, Department of General Surgery, Gazi University, Besevler, Ankara, Turkey.
In obesity, the process of adipogenesis largely determines the number of adipocytes in body fat depots. Adipogenesis is regulated by several adipocyte-selective micro-ribonucleic acids (miRNAs) and transcription factors that modulate adipocyte proliferation and differentiation. However, some miRNAs block the expression of master regulators of adipogenesis.
View Article and Find Full Text PDFEffects of liver X receptor in O3-induced airway inflammation and remodeling in mice.
J Thorac Dis
August 2024
Department of Respiratory Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Article Synopsis
- The study investigates the role of Liver X receptors (LXRs) in protecting against airway inflammation and remodeling caused by ozone exposure in mice, as current COPD treatments do not reverse disease progression.
- Results showed that LXR deficient mice experienced more severe airway issues and inflammation, evidenced by increased inflammatory proteins and foamy macrophages compared to normal mice.
- Treatment with a LXR agonist in wild mice reduced airway inflammation and remodeling, suggesting that LXRs may have a protective effect against ozone-induced damage.
M2 macrophages play an important role in food allergy. Several studies have reported that lactic acid bacteria isolated from pickles exert antiallergic effects. We investigated the effects of several strains of lactic acid bacteria on the immune function of M2 macrophages.
View Article and Find Full Text PDFGene Expression of Neurogenesis Related to Exercise Intensity in a Cerebral Infarction Rat Model.
Int J Mol Sci
August 2024
Department of Physical & Rehabilitation Medicine, Chonnam National University Medical School, #160, Baekseo-ro, Dong-gu, Gwangju 61469, Republic of Korea.
Regular exercise improves several functions, including cognition, in patients with stroke. However, the effect of regular exercise on neurogenesis related to cognition remains doubtful. We investigated the most effective exercise intensity for functional recovery after stroke using RNA sequencing following regular treadmill exercise.
View Article and Find Full Text PDFMethylation of Interleukin-1 receptor-associated kinase-3 and the risk of multiple sclerosis relapse/activity.
Clin Immunol
September 2024
Neurology department, Faculty of Medicine. Tanta University, Tanta 31527, Egypt.
This study retrospectively investigated the impact of interleukin-1 receptor-associated kinase-3 (IRAK-3/IRAK-M) silencing by methylation on the likelihood of multiple sclerosis (MS) activity. This cross-sectional study included 90 patients with MS: 45 with active disease (Group 1), 45 in remission (Group 2), and 45 healthy controls. The study included quantitation of IRAK-3 methylation index (MI%), IRAK-3 mRNA, and myeloid differentiation factor88 (MyD88) and assessment of NF-κB activity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!