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| http://dx.doi.org/10.1136/bcr-2013-200658 | DOI Listing |
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The influence of serum uric acid on coronary atherosclerosis plaque phenotypes by computed tomography angiography: The missing link?
Nutr Metab Cardiovasc Dis
December 2024
Department of Radiology, Innsbruck Medical University, Innsbruck, Austria. Electronic address:
Background And Aims: The interaction of serum uric acid (SUA) with atherogenesis is incompletely understood. Aim of our study was to investigate the association of SUA levels with coronary plaque composition including high-risk-plaque (HRP) features by coronary computed tomography angiography (CTA) and for the prediction of major adverse cardiac events (MACE).
Methods And Results: 1242 patients (age 66.
Iron levels and vulnerable coronary atherosclerotic plaques.
Kardiol Pol
January 2025
Department of Coronary and Structural Heart Diseases, National Institute of Cardiology, Warszawa, Poland.
Background: Preliminary research indicates that higher iron levels are associated with worse outcomes in patients with coronary artery disease.
Aims: The study aimed to investigate the relationship between iron levels and the type and composition of coronary plaques.
Methods: In patients with ≥1 coronary stenosis ≥50% on computed tomography angiography, iron levels, presence of high-risk plaque features, such as low-attenuation plaque (LAP), napkin-ring sign, positive remodeling, and spotty calcium, as well as type and plaque composition (calcified/fibrous/fibro-fatty/necrotic core) were evaluated.
Reduced voltage-activated Ca2+ release flux in muscle fibers from a rat model of Duchenne dystrophy.
J Gen Physiol
March 2025
University Lyon, Université Claude Bernard Lyon 1, CNRS UMR-5261, INSERM U-1315, Institut NeuroMyoGène - Pathophysiology and Genetics of Neuron and Muscle , Lyon, France.
The potential pathogenic role of disturbed Ca2+ homeostasis in Duchenne muscular dystrophy (DMD) remains a complex, unsettled issue. We used muscle fibers isolated from 3-mo-old DMDmdx rats to further investigate the case. Most DMDmdx fibers exhibited no sign of trophic or morphology distinction as compared with WT fibers and mitochondria and t-tubule membrane networks also showed no stringent discrepancy.
View Article and Find Full Text PDFAssessing correlation between different temporary restorative materials for microleakage following endodontic treatment: an in-vitro study.
BMC Oral Health
December 2024
Department of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 600077, Tamil Nadu, India.
Background: Coronal microleakage, the passage of fluids and bacteria through the interface between the temporary restoration and the tooth structure, can potentially result in endodontic treatment failure.
Purpose: This study evaluated and compared the sealing efficacy of various temporary restorative materials utilized during endodontic procedures.
Methods: All seventy premolar teeth were extracted, measured, and restored, except for the negative control group, where the teeth were left whole.
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