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Percutaneous ballon compression, a better choice for primary trigeminal neuralgia compared to microvascular decompression?
Front Surg
January 2025
Department of Neurosurgery, Ward 2. Gansu Provincial Hospital, Lanzhou, Gansu, China.
Objective: Demonstrate the superiority of percutaneous balloon compression (PBC) in the treatment of primary trigeminal neuralgia (PTN) compared to trigeminal microvascular decompression (MVD).
Methods: Clinical data, including immediate, short-term, and long-term pain relief, complications, duration of the operation, and postoperative hospital stay, were retrospectively analyzed for 114 patients diagnosed with PTN who were treated with either PBC or MVD between January 2018 and December 2021.
Results: There were no statistically significant differences observed in the pain relief rates between the two surgical methods at 24 h postoperatively (MVD: 91.
The effect of a mindfulness-based cognitive therapy program on the spiritual health of mothers of infants admitted to the neonatal intensive care unit.
Front Psychol
January 2025
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Introduction: The birth and admission of a premature infant to the NICU is often an unexpected experience and a mental and spiritual challenge for families. Spiritual health is an influential factor affecting how a mother faces and endures a stressful situation. Improving the mother's spiritual health requires cognitive therapy approaches, including mindfulness techniques.
View Article and Find Full Text PDFInvestigating resistance to 5-Azacytidine and Venetoclax in PDX models of MDS/AML.
Front Oncol
January 2025
BIOCEV, First Faculty of Medicine, Charles University, Prague, Czechia.
Introduction: Progressing myelodysplastic syndrome (MDS) into acute myeloid leukemia (AML) is an indication for hypomethylating therapy (HMA, 5-Azacytidine (AZA)) and a BCL2 inhibitor (Venetoclax, VEN) for intensive chemotherapy ineligible patients. Mouse models that engraft primary AML samples may further advance VEN + AZA resistance research.
Methods: We generated a set of transplantable murine PDX models from MDS/AML patients who developed resistance to VEN + AZA and compared the differences in hematopoiesis of the PDX models with primary bone marrow samples at the genetic level.
The prediction value of serum anion gap for short-term mortality in pulmonary hypertension patients with sepsis: a retrospective cohort study.
Front Med (Lausanne)
January 2025
Department of Cardiology, Hunan Children's Hospital Affiliated to Jinan University, Changsha, China.
Background: The relationship between anion gap (AG) and short-term mortality of pulmonary hypertension (PH) patients with sepsis in the intensive care unit (ICU) remains unclear.
Methods: This study involved a retrospective analysis of incident PH patients with sepsis first admitted to the ICU in the MIMIC IV database (2008 to 2019). Short-term outcomes include in-hospital mortality and 28-day mortality.
Association of the blood urea nitrogen to serum albumin ratio and all-cause mortality in critical ill acute ischemic stroke patients: a retrospective cohort study of MIMIC-IV database 3.0.
Front Nutr
January 2025
Department of Immunology, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China (UESTC), Mianyang, Sichuan, China.
Purpose: We aim to ascertain the extent to which the blood urea nitrogen (BUN) to serum albumin (ALB) ratio (BAR) could be implemented to anticipate the short- and long-term prognosis of acute ischemic stroke (AIS) patients in intensive care units (ICUs).
Methods: The data was derived from the Marketplace for Intensive Care Medical Information-IV (MIMIC-IV v3.0) database, primarily pertaining to AIS patients as categorized by the International Classification of Diseases (ICD)-9 and ICD-10.
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