Design, synthesis and evaluation of a boronic acid based artificial receptor for (L)-DOPA in aqueous media.

Chem Commun (Camb)

Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.

Published: November 2013

Design and synthesis of a boronic acid based artificial receptor which selectively and effectively bound to a neurotransmitter, l-DOPA (), in aqueous media. In addition, the synthetic receptor was found to effectively inhibit the DDC (l-DOPA decarboxylase) enzymatic reaction under physiological conditions.

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http://dx.doi.org/10.1039/c3cc45275aDOI Listing

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