Surgical timing of craniosynostosis: what to do and when.

J Craniomaxillofac Surg

Department of Maxillo-Facial Surgery, Policlinico Umberto I, Sapienza University of Rome, Piazzale Aldo Moro 9, 00185 Rome, Italy.

Published: July 2014

Craniosynostosis, both isolated and syndromic, are challenging malformations for the craniofacial team. They present the team with an articulated cascade of choices, which need to be addressed early in life and in the growing age to intercept, remove, or correct the direct and indirect consequences of the malformation. Timing of treatment is thus critical and it stands on the experience of a multi-specialty trained craniofacial team. In this paper the authors discuss the timing of treatment of the major craniosynostosis, isolated and syndromic, reviewing the options for treatment and their experience in this complex field.

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http://dx.doi.org/10.1016/j.jcms.2013.07.018DOI Listing

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Article Synopsis
  • The study investigates the effectiveness of a surgical procedure (extended strip craniectomy with bilateral barrel staving) for treating isolated craniosynostosis of the sagittal suture in infants, specifically focusing on its impact on cranial shape without directly addressing forehead issues.
  • Results showed significant improvements in aspects like bossing angle and cephalic index over a year, although the cranial shape did not entirely match that of healthy peers, indicating partial normalization but not complete correction.
  • The research validates 3D photogrammetry as a useful noninvasive tool for assessing cranial changes post-surgery, suggesting potential for wider clinical applications in monitoring cranial morphology.
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Methods: A retrospective cohort study was conducted at a tertiary pediatric surgery center, involving all 45 patients treated surgically for isolated sagittal craniosynostosis from 2013 to 2024.

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Introduction: Craniosynostosis, marked by premature skull suture closure, manifests as isolated or syndromic cases. While isolated cases are more common, syndromic craniosynostoses are associated with a range of complications. This study aims to compare postoperative outcomes in isolated and syndromic craniosynostosis, hypothesizing greater complications in the latter.

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Craniosynostosis is a congenital abnormality resulting in the premature fusion of one or more cranial sutures and usually requires surgical correction in the first year of life. While the majority of craniosynostosis cases represent isolated, nonsyndromic defects, approximately 25% are linked to a genetic diagnosis. Craniosynostosis has been associated with developmental delay.

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Craniosynostosis is characterized by the premature fusion of one or more cranial sutures, which can lead to abnormal skull shape and restricted skull growth. Although most cases are present in isolation, some are associated with genetic syndromes, such as Pfeiffer, Muenke, Couzon, Apert, and others, which increases the complexity of care. Today, a spectrum of surgical options to treat craniosynostosis are available and range from traditional open cranial vault remodeling to newer and less invasive suturectomy-based techniques.

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