A three-dimensional culture of cortical tissues derived from pluripotent stem cells offers an opportunity to model human brain development and disorders. In a recent issue of Nature, Lancaster et al. describe a new method for generating cerebral organoids in a dish and use it to model microcephaly.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127703 | PMC |
| http://dx.doi.org/10.1016/j.cell.2013.09.010 | DOI Listing |
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