AI Article Synopsis

  • Primary hyperaldosteronism is a common cause of secondary hypertension, leading to higher cardiovascular risks compared to essential hypertension, necessitating diagnosis and treatment.
  • Treatment options include medical management with mineralocorticoid receptor antagonists or surgical adrenalectomy, with pre-surgical evaluations required.
  • Surgery can normalize potassium levels and reduce blood pressure in 50-88% of patients, with 30% able to discontinue medication, while both treatment methods effectively lower cardiovascular risks if blood pressure is well-controlled.

Article Abstract

Primary hyperaldosteronism is one of the most frequent causes of secondary hypertension. Cardiovascular morbimortality is higher than in essential hypertonic and justifies diagnostic and specific treatment of this pathology. Therapeutic choice depends of health and desire of the patient. It is either medical with mineralocorticoid receptor antagonists, or surgical through adrenalectomy. In this case, a pre-surgery exam including a radiologic examination and a venous adrenal catheterism has to be done. Surgery allows a normalisation of kaliema and a blood pressure decrease in 50 to 88% of the patients. Beyond them, 30% are able to stop entirely their medication. Both therapeutic choices decrease cardiovascular risks equally if blood pressure is controlled.

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