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http://dx.doi.org/10.1007/s00216-013-7343-x | DOI Listing |
Anal Bioanal Chem
November 2013
Université de Bordeaux, Inserm U1029, Avenue des Facultés, Bat. B2, 33405, Talence-Cedex, France,
Anal Bioanal Chem
November 2013
Laboratoire d'Ingénierie de Surface (LIS), Département de Génie des Mines, de la Métallurgie et des Matériaux, Centre de Recherche sur les Matériaux Avancés (CERMA), Université Laval, 1065 avenue de la médecine, Québec, QC, G1V 0A6, Canada.
The skin acts mainly as a protective barrier from the external environment, thanks to the stratum corneum which is the outermost layer of the skin. As in vitro tests on skin are essential to elaborate new drugs, the development of skin models closer to reality becomes essential. It is now possible to produce in vitro human skin substitutes through tissue engineering by using the self-assembly method developed by the Laboratoire d'Organogénèse Expérimentale.
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