AI Article Synopsis
Article Abstract
Analytical derivatization either in pre or post column modes is one of the most widely used sample pretreatment techniques coupled to liquid chromatography. In the present review article we selected to discuss the post column derivatization mode for the analysis of organic compounds. The first part of the review focuses to the instrumentation of post-column setups including not only fundamental components such as pumps and reactors but also less common parts such as static mixers and back-pressure regulators; the second part of the article discusses the most popular "chemistries" that are involved in post column applications, including reagent-less approaches and new sensing platforms such as the popular gold nanoparticles. Some representative recent applications are also presented as tables.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.aca.2013.07.032 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Biomechanical simulation of bed turning post-acetabular fracture fixation.
Sci Rep
January 2025
Department of Orthopaedic, South China Hospital of Shenzhen University, Shenzhen, 518116, Guangdong, China.
Before patients begin out-of-bed exercises following internal fixation surgery for acetabular fractures, turning over in bed serves as a crucial intervention to mitigate complications associated with prolonged bed rest. However, data on the safety of this maneuver post-surgery are limited, and the biomechanical evidence remains unclear. This study aims to introduce a novel loading protocol designed to preliminarily simulate the action of turning over in bed and to compare the biomechanical properties of two fixation methods for acetabular fractures under this new protocol.
View Article and Find Full Text PDFA sensitive post-column derivatization approach for enhancing hydroxyl metabolites detection.
Anal Chim Acta
February 2025
Department of Pharmacy, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan. Electronic address:
Background: Chemical derivatization is a common technique in liquid chromatography-mass spectrometry (LC-MS) metabolomics used to improve the ionizability and chromatographic properties of metabolites in complex biological samples. This process facilitates better detection and separation of a wide array of compounds. The reagent 2-(4-boronobenzyl) isoquinolin-2-ium bromide (BBII), developed as a glucose labeling reagent for matrix-assisted laser desorption/ionization MS, enhances ionization for glucose and other hydroxyl metabolites.
View Article and Find Full Text PDFStudy on the mechanical response characteristics of sandstone under elasticity plasticity and full path unloading after peak stress.
Sci Rep
January 2025
Heilongjiang Ground Pressure and Gas Control in Deep Mining Key Laboratory, Heilongjiang University of Science and Technology, Harbin, 15002, China.
When underground tunnels in coal mines traverse geological structurally abnormal zones (faults, collapse columns, fractured zones, etc.), excavation-induced unloading leads to instability and failure of the engineering rock mass. Rock masses in fractured zones are in elastic, plastic, and post-peak stress states, and the process of excavation through these zones essentially involves unloading under full stress paths.
View Article and Find Full Text PDFPhase-specific changes in hip joint loading during gait following sacroiliac joint fusion: Findings from a finite element analysis.
Clin Biomech (Bristol)
January 2025
Ohio State University Wexner Medical Center, Department of Orthopaedics, Columbus, OH, USA. Electronic address:
Background: Low back pain affects over 80 % of adults, with sacroiliac joint dysfunction accounting for 15-30 % of these cases. Sacroiliac fusion is a surgical procedure for refractory joint pain. While the biomechanics of the joint and its fusion relative to the spinal column are well-known, the hip-spine relationship post-fusion remains unclear.
View Article and Find Full Text PDFDifferential homing of monocytes and neutrophils in the epithelial layer of HSV-1 infected cornea regulates viral dissemination and wound healing.
Ocul Surf
January 2025
Department of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, MI, USA. Electronic address:
Purpose: To ascertain the homing of monocytes and neutrophils in the epithelium versus stroma of HSV-1 infected corneas at different stages of infection and functional significance of their anatomical location in virus-infected corneas.
Methods: The corneas of C57BL/6J mice were infected with HSV-1 McKrae. Mice were euthanized on different days post-infection.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!