Objective: The aim of this epidemiological, data-based survival study was to study the longevity of restorations in permanent molars of adolescents in the 1990 and 1995 birth cohorts during the period of 1992-2005 in the City of Vantaa, Finland.
Materials And Methods: The dental records of 2975 (1990 cohort) and 3147 (the 1995 cohort) adolescents were analyzed. The longevity of restorations from their placement until replacement was illustrated using the Kaplan-Meier survival curves. The influence of the cohort, gender and caries risk on the survival rate was assessed using the Cox proportional hazards regression analysis.
Results: A majority of the restorations were tooth-colored. The proportion of amalgam restorations was almost non-existent in both cohorts. The survival of tooth-colored restorations on the occlusal surfaces of molars was lower in the 1995 cohort compared to the 1990 cohort. The need of replacement of glass-ionomer restorations was twice that of composite restorations' hazard ratio 2.27 (1.62-3.16).
Conclusions: Composites are the most frequently used dental materials and have the longest survival times among adolescents. The survival of restorations per se is poorer in the more recent than in the earlier birth cohort.
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http://dx.doi.org/10.3109/00016357.2013.844270 | DOI Listing |
JCI Insight
January 2025
Department of Nephrology, Blood Purification Research Center, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Renal osteodystrophy is commonly seen in patients with chronic kidney disease (CKD) due to disrupted mineral homeostasis. Given the impaired renal function in these patients, common anti-resorptive agents, including bisphosphonates, must be used with caution or even contraindicated. Therefore, an alternative therapy without renal burden to combat renal osteodystrophy is urgently needed.
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Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 9017 - CIIL - Center for Infection and Immunity of Lille, F-59000 Lille, France.
Atomic force microscopy (AFM) has reached a significant level of maturity in biology, demonstrated by the diversity of modes for obtaining not only topographical images but also insightful mechanical and adhesion data by performing force measurements on delicate samples with a controlled environment (e.g., liquid, temperature, pH).
View Article and Find Full Text PDFNeuropsychol Rehabil
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School of Psychological Sciences, Macquarie University, Marsfield, NSW 2109, Australia.
Prosopagnosia is a neurological disorder; characterized by an impairment in facial recognition. It can occur from acquired prosopagnosia (occurring in approximately 5.6% of the population), or from developmental prosopagnosia (occurring in approximately 2% of the population).
View Article and Find Full Text PDFProbiotics Antimicrob Proteins
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Department of Food Science and Technology, Faculty of Nutrition & Food Sciences, Nutrition, Tabriz, Iran.
Infertility poses a global challenge that impacts a significant proportion of the populace. Presently, there is a substantial emphasis on investigating the potential of probiotics and their derivatives, called postbiotics, as an alternative therapeutic strategy for addressing infertility. The term of "postbiotics" refers to compounds including peptides, enzymes, teichoic acids, and muropeptides derived from peptidoglycans, polysaccharides, proteins, and organic acids that are excreted by living bacteria or released after bacterial lysis.
View Article and Find Full Text PDFJ Muscle Res Cell Motil
January 2025
Institute of Developmental and Regenerative Medicine, University of Oxford, IMS-Tetsuya Nakamura Building, Old Road Campus, Roosevelt Dr, Headington, Oxford, OX3 7TY, UK.
Recent years have seen enormous progress in the field of advanced therapeutics for the progressive muscle wasting disease Duchenne muscular dystrophy (DMD). In particular, four antisense oligonucleotide (ASO) therapies targeting various DMD-causing mutations have achieved FDA approval, marking major milestones in the treatment of this disease. These compounds are designed to induce alternative splicing events that restore the translation reading frame of the dystrophin gene, leading to the generation of internally-deleted, but mostly functional, pseudodystrophin proteins with the potential to compensate for the genetic loss of dystrophin.
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