Visual outcomes of Femto-LASIK for correction of residual refractive error after corneal graft.

Purpose: To evaluate the outcomes of the Femto-LASIK method in the treatment of refractive errors following penetrating keratoplasty (PK) at the Persian Eye Clinic, Isfahan, Iran

Methods: In a prospective, non-comparative case series, 34 consecutive symptomatic eyes of 34 patients after corneal graft, were operated on. Tissue-saving (TS) Femto-LASIK (n = 16), and Zyoptix Personalized Treatment Advanced (PTA) Femto-LASIK (n = 18) were performed using the Bausch & Lomb Technolas 217z excimer laser and Zyoptic algorithm. Uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), manifest refraction, contrast sensitivity, and HOAs were evaluated preoperatively and 12 months after enhancement treatment.

Results: At 12 months, the mean preoperative myopic spherical equivalent refraction (SE) decreased from -6.50 ± 2.8 D to -1.6 ± 1.8 D, and mean hyperopic SE from +3.2 ± 2.20 D to 0.37 ± 1.2 D. The safety index was 1.42 (1.2 in the TS group and 1.5 in the PTA group). In the TS group, 100% of eyes achieved 20/80 or better UCVA and 50%, 20/40 or better and in the PTA group, 100% of eyes achieved 20/80 or better UCVA and 77.7%, 20/40 or better. The efficacy index was 1.08 (0.9 in TS group and 1.21 in the PTA group). Patients obtained statistically significant lower values of root mean square (RMS) of HOAs with spherical aberrations (p < 0.05).

Conclusions: Femto-LASIK method with Zyoptic programs after PK was safe, effective, and predictable for correction of spherical and cylindrical components of the refractive error.