Norovirus genogroup II gastroenteritis in hospitalized children in South India.

Am J Trop Med Hyg

Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India; Departments of Child Health Units I, II and III, Christian Medical College, Vellore, India.

Published: November 2013

The distribution of norovirus (NoV) genogroup II in children < 5 years of age admitted to a south Indian hospital with diarrhea was investigated. Viral RNA extracted from 282 stool samples were screened for NoV GII and positive amplicons sequenced. Twenty-eight (9.9%) had NoV GII infection with a median age of 6 months, with more severe episodes of diarrhea among infected (median Vesikari score 13, interquartile range [IQR] 10-15) than children without infection (median score 10, IQR 8-13, P = 0.002). The study documents NoV GII infections as an important cause of gastroenteritis and the genetic diversity of circulating strains.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820314PMC
http://dx.doi.org/10.4269/ajtmh.13-0121DOI Listing

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