Localization of smooth muscle myosin-containing cells in the aqueous outflow pathway.

Invest Ophthalmol Vis Sci

Eye Research Institute, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston.

Published: February 1990

AI Article Synopsis

  • Smooth muscle myosin was identified in the human aqueous outflow pathway using immunohistochemical techniques, primarily found near collector channels and Schlemm's canal.
  • Some instances showed smooth muscle myosin in juxtacanalicular tissue and trabecular meshwork, possibly indicating the presence of smooth muscle cells or pericytes.
  • There were no significant differences in the distribution of these myosin-containing cells across different age groups, and a direct connection was noted between the ciliary muscle and the corneoscleral meshwork.

Article Abstract

Cells containing smooth muscle myosin were localized in the human aqueous outflow pathway by immunohistochemical techniques. In the majority of eyes, immunoreactive cells were observed adjacent to the collector channels and slightly distal to the outer wall of Schlemm's canal. In a few eyes, smooth muscle myosin was localized to cells in the juxtacanalicular tissue and the trabecular meshwork. The immunoreactive cells from these regions may be true smooth muscle cells or pericytes, which can contain smooth muscle myosin. No obvious differences were observed in the pattern of distribution of smooth muscle myosin-containing cells in a comparison of age groups. In the majority of eyes, we observed an apparent direct insertion of the longitudinal portion of the ciliary muscle in the corneoscleral meshwork far internal to the scleral spur.

Download full-text PDF

Source

Publication Analysis

Top Keywords

smooth muscle
24
muscle myosin
12
muscle myosin-containing
8
myosin-containing cells
8
aqueous outflow
8
outflow pathway
8
myosin localized
8
majority eyes
8
immunoreactive cells
8
muscle
7

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!