Two new Schiff base ligands 4-[(1E)-(3,4-dimethoxyphenyl)methylene]amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (1) and 4-[(1E)-(2-hydroxy-5-methoxyphenyl)methylene]amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (2) have been prepared and characterized using elemental analysis, UV-vis, FT-IR, 1H and 13C NMR spectroscopy, and X-ray crystallographic technique. Tautomeric equilibria (phenol-imine, O-H...N and keto-amine, O...H-N forms) have been studied by using UV-vis absorption spectra for the compound 2 in some solutions. Crystal structure analyses showed that the title molecules 1 and 2 crystallize in the monoclinic space group P21/c and P21 with the unit cell parameters: a = 12.5665(3) Å and 5.6666(2) Å; b = 10.4791(2) Å and 12.2444(5) Å; c = 14.6240(3) Å and 12.1556(4) Å; V =1820.65(7) Å3 and 826.84(5) Å3; Dx = 1.282 g.cm-3 and 1.355 g.cm-3; and Z = 4 and 2, respectively.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Fluorometric Turn Off Detection of Cu and Pd Ions Using 1-(Imidazo[5,1-a]isoquinolin-3-yl)naphthalen-2-ol.
Luminescence
January 2025
Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam, India.
The fused heterocycle 1-(imidazo[5,1-a]isoquinolin-3-yl)naphthalen-2-ol (LH) has been synthesized and characterized by spectroscopic methods. Probe LH upon irradiation with λ = 336 nm exhibited strong fluorescence with λ = 437 nm in MeOH/HEPES buffer (5 mM, pH = 7.4, 2:8, v/v).
View Article and Find Full Text PDFSynthesis of Some Thiazolyl and Oxazolyl Quinazoline Derivatives as Potential Anti-Microbial Agents.
Curr Org Synth
January 2025
Department of Chemistry, Constituent Govt. College, (MJP. Rohilkhand University Bareilly) Hasanpur, (UP), 244241, India.
Introduction: Quinazoline holds significant importance in pharmaceutical chemistry, which is included in a range of drugs, clinical contenders, and bioactive compounds. N-contain-ing heterocyclic compounds of quinazoline have a wide and distinct range of biopharmaceutical activities.
Methods: A series of newly synthesized heterocyclic compounds, namely, N-(4-substituted ben-zylidene)-2-(2-aminothiazol-4-yl)-6-methylquinazolin-3(4H)-amines (3a'-3e') and N-(4-substi-tuted benzylidene)-2-(2-aminooxazol-4-yl)-6-methylquinazolin-3(4H)-amines (3a-3e), were synthesized starting from 6-methylquinazolin-3(4H)-amine and 4-substituted benzaldehyde and their antibacterial and antifungal properties were evaluated.
Elucidation on the Interaction Between Transferrin and Tetrachlorobisphenol A Based on Multispectroscopic Analysis, Molecular Docking Technique, and Conformational Studies.
Luminescence
January 2025
School of Chemistry and Chemical Engineering, Nanchang University, Nanchang, Jiangxi, China.
Tetrachlorobisphenol A (TCBPA) is a kind of fire retardant extensively used in our life, but it can accumulate in organisms and potentially have toxic effects. Transferrin (TF) is a glycoprotein predominantly present in the blood plasma, serving as an essential mediator for the transportation of iron and other small molecules. In our study, various techniques including multi-spectroscopic and molecular docking were employed to examine the interaction between TCBPA and TF.
View Article and Find Full Text PDFCross-Coupling Reactions with Nickel, Visible Light, and -Butylamine as a Bifunctional Additive.
ACS Catal
January 2025
Fakultät für Chemie und Pharmazie, Universität Regensburg, Regensburg 93040, Germany.
Transition metal catalysis is crucial for the synthesis of complex molecules, with ligands and bases playing a pivotal role in optimizing cross-coupling reactions. Despite advancements in ligand design and base selection, achieving effective synergy between these components remains challenging. We present here a general approach to nickel-catalyzed photoredox reactions employing -butylamine as a cost-effective bifunctional additive, acting as the base and ligand.
View Article and Find Full Text PDFIn vivo two-photon FLIM resolves photosynthetic properties of maize bundle sheath cells.
Photosynth Res
January 2025
State Key Laboratory of Forage Breeding-by-Design and Utilization, Key Laboratory of Photobiology, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.
Maize (Zea mays L.) performs highly efficient C photosynthesis by dividing photosynthetic metabolism between mesophyll and bundle sheath cells. In vivo physiological measurements are indispensable for C photosynthesis research as photosynthetic activities are easily interrupted by leaf section or cell isolation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!