AI Article Synopsis
- The study investigated the link between Chlamydia trachomatis (CT) infection and the risk of developing preeclampsia in a group of 205 affected women and 423 healthy controls.
- Serological testing for CT was conducted at the first prenatal visit (around 14 weeks) and again at delivery, with a focus on detecting prenatal infections through specific antibody responses.
- Though only a small percentage of the pregnant women showed signs of new CT infections, those who did were significantly more likely to experience preeclampsia, even after accounting for other factors like age and body mass index.
Article Abstract
The relationship between (CT) and preeclampsia was examined longitudinally among 205 cases and 423 normotensive controls nested within the Collaborative Perinatal Project. Antibodies were analyzed at a first prenatal visit (mean 14.2 weeks) and at delivery. Prenatal infections were identified as IgG/IgM seroconversion or a four-fold rise in IgG antibody titers. Although serological evidence of incident prenatal CT infection was uncommon (n=9, 1.4%) in this general pregnant population, infected women were more likely to develop preeclampsia, after adjustment for maternal age, body mass index, smoking status, race and time between blood draws (OR 7.2, 95% CI 1.3 - 39.7).
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775369 | PMC |
| http://dx.doi.org/10.1016/j.preghy.2013.03.002 | DOI Listing |
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