Objectives: We evaluated the association of plasma uric acid alone and in combination with b-type natriuretic peptide (BNP) for emergency department (ED) diagnosis and 30-day prognosis in patients evaluated for acute heart failure (AHF).

Methods: We prospectively enrolled 322 adult ED patients with suspected AHF. Wilcoxon rank sum test, multivariable logistic regression and likelihood ratio (LR) tests were used for statistical analyses.

Results: Uric acid's diagnostic utility was poor and failed to show significant associations with 30-day clinical outcomes. Uric acid also did not add significantly to BNP results.

Conclusion: Among ED patients with suspected AHF, uric acid has poor diagnostic and prognostic utility.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777695PMC
http://dx.doi.org/10.2174/1875318301205010009DOI Listing

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