Rearrangements affecting the long arm of chromosome 3 have been linked to abnormalities of platelet production and morphology in hematologic disorders. We present five patients with myelodysplastic syndromes or acute leukemia in whom inv(3)(q21q26) was seen. One of the patients showed an inversion of both homologs involving precisely the same breakpoints, suggesting apparent duplication of the abnormal chromosome 3 and loss of the normal homolog. To our knowledge this is the first report detailing such a condition.
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Article Synopsis
- - The text discusses the growing interest in large language models (LLMs) in medical contexts, emphasizing the need to evaluate their accuracy on healthcare examinations relative to established human performance standards.
- - A systematic review of literature up to September 2023 was conducted, analyzing the accuracy of LLMs in responding to healthcare examination questions, with a strict inclusion criterion to ensure relevant and original research.
- - The findings indicated that LLMs had an overall medical exam accuracy of 0.61 and a USMLE accuracy of 0.51, highlighting a significant gap compared to human performance metrics in medical assessments.
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