AI Article Synopsis
- 62 Mycobacterium tuberculosis strains were analyzed using fast ligation-mediated PCR (FLiP) and IS6110 RFLP methods.
- FLiP demonstrated high reproducibility and specificity for distinguishing between different M. tuberculosis strains.
- The discriminatory capability of FLiP was nearly equivalent to the IS6110 RFLP method, indicating its potential for researching the genetic diversity of M. tuberculosis strains.
Article Abstract
In this study, 62 Mycobacterium tuberculosis strains were characterized by fast ligation-mediated PCR (FLiP) and, previously performed, IS6110 restriction fragment length polymorphism (RFLP). FLiP proved a reproducible and specific method for differentiation between M. tuberculosis strains. The discriminatory power of FLiP was close to that of the reference IS6110 RFLP suggesting its usefulness in studying the genetic diversity of M. tuberculosis strains.
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