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Estimating eGFR using serum creatinine or cystatin C in healthy Vietnamese population.
Medicine (Baltimore)
May 2024
Can Tho University of Medicine and Pharmacy, Can Tho City, Vietnam.
Very few studies worldwide have assessed the estimated glomerular filtration rate (eGFR) using serum cystatin C (ScysC) in comparison to the gold standard measured glomerular filtration rate (mGFR) with a gamma camera technique using 99m-Technetium-Diethylene Triaminepentoacetic Acid (99mTc-DTPA). To determine the eGFR formula with the most accurate estimate of glomerular filtration rate when compared with mGFR in a healthy population in Vietnam. We conducted a cross-sectional descriptive study of more than 100 adults without hypertension.
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- - The study was a scoping review following PRISMA guidelines, aimed at evaluating literature on urinary and renal system monitoring in people with spinal cord injuries (SCI), focusing on methods of surveillance and risk factors for urinary tract abnormalities.
- - 685 studies were initially reviewed, with findings indicating that serum cystatin C (s-cysC) is a reliable measure for glomerular filtration rate, while adherence to surveillance does not significantly impact the development of urinary tract abnormalities over time.
- - The research concludes that s-cysC is preferable to serum creatinine for kidney function assessment and suggests targeted surveillance strategies based on individual risk profiles for better patient care.
[Applicability of Seven Glomerular Filtration Rate Evaluation Formulas in Dose Adjustment of High Concentration of Methotrexate Chemotherapy in Children with ALL].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
February 2023
Department of Laboratory Medicine, Cancer Hospital of Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, Anhui Province, China,E-mail:
Article Synopsis
- The study aimed to evaluate the effectiveness of seven different formulas for estimating glomerular filtration rate (GFR) in children with acute lymphoblastic leukemia (ALL) undergoing high-dose methotrexate (HDMTX) chemotherapy, focusing on a GFR cutoff of 85 ml/min.
- A total of 124 children with ALL were examined, using renal dynamic imaging (sGFR) as the standard for comparison of the estimated GFR (eGFR) values calculated by the seven formulas.
- The results indicated that the Schwartz2009 formula provided the highest accuracy across various age groups, while CKD-EPI, Filler, and Cockrofi-Gault formulas also showed significant reliability for HDMTX dose
Epidemiology and renal injury following 2-methyl-4-chlorophenoxyacetic acid (MCPA) poisoning.
Sci Rep
December 2022
South Asian Clinical Toxicology Research Collaboration, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
2-Methyl-4-chlorophenoxyacetic acid (MCPA) is a widely used chlorophenoxy herbicide. MCPA poisoning causes mitochondrial dysfunction, which can lead to kidney injury and death. The objective of this study is to describe the epidemiology, case fatality and extent of renal injury in a large cohort of MCPA self-poisonings.
View Article and Find Full Text PDFApplicability of 14 Formulas for Estimating Glomerular Filtration Rate in the Evaluation of Renal Function before and after Nephron-Sparing Surgery in Patients with Renal Tumors.
Contrast Media Mol Imaging
May 2022
Shengli Clinical Medical College of Fujian Medical University and Department of Urology, Fujian Provincial Hospital, Fuzhou 350001, China.
To compare the applicability of 14 equations of estimating glomerular filtration rate (eGFR) before and after nephron-sparing surgery (NSS) for renal function assessment of patients with renal tumors. Preoperative and postoperative GFR is measured by emission computed tomography (ECT) with 99mTc-DTPA as an imaging agent as reference GFR (rGFR) to compare with all formulas. Spearman correlation analysis and Bland-Altman agreement analysis were used to evaluate the correlation between rGFR and eGFR1 to 14 before and after surgery.
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