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A passerini-type condensation: a carboxylic acid-free approach for the synthesis of the α-acyloxycarboxamides. | LitMetric

A passerini-type condensation: a carboxylic acid-free approach for the synthesis of the α-acyloxycarboxamides.

Comb Chem High Throughput Screen

Faculty of Chemistry, Shahid Beheshti University, G. C., P. O. Box 19396-4716, Tehran, Iran.

Published: December 2013

A Passerini-type condensation for the synthesis of α-acyloxycarboxamides starting from simple and readily available inputs, including an isocyanide, aldehydes and water in the presence of trimethylsilyl azide as a catalyst under reflux conditions in toluene in good yields, is described.

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Source
http://dx.doi.org/10.2174/13862073113169990051DOI Listing

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