We present a miniature endomicroscope that combines large field-of-view (FOV) (1.15 mm) reflectance imaging with high-resolution (~0.5 μm) multiphoton intrinsic fluorescence imaging. We acquired in vivo and ex vivo images of unstained normal and tumor-laden tissues by using the large-FOV mode to navigate to the site of interest and then switching to the high-resolution modality to resolve cellular details.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771821 | PMC |
| http://dx.doi.org/10.1364/BOE.4.001494 | DOI Listing |
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