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An Oral Microbial Biomarker for Early Detection of Recurrence of Oral Squamous Cell Carcinoma.
ACS Infect Dis
September 2023
Institute of Biotechnology, National Taiwan University, Taipei 10617, Taiwan.
Article Synopsis
- Changes in the oral microbiome are linked to oral squamous cell carcinoma (OSCC) recurrence, with specific microbial signatures identified as potential biomarkers for predicting recurrence.
- A study analyzed oral swab samples from OSCC patients and found significant differences in bacterial compositions between those with and without recurrence, highlighting certain microbes that were enriched in recurring cases.
- A prediction model using five microbial signatures showed high accuracy in distinguishing OSCC recurrence, performing better than traditional clinical indicators, thus suggesting a promising noninvasive approach for OSCC prognosis and treatment.
: Case Report and Review of the Literature on Patients with Bacteremia in Acute Myeloid Leukemia.
Infect Disord Drug Targets
August 2023
HCA Las Palmas/Del Sol Internal Medicine Program, El Paso, Texas, USA.
Background: Leptotrichia spp. are fastidious facultative anaerobic, pencil-shaped, gramnegative rods that reside in the mouths, intestines, and female genital tracts of humans. Bacteremia and septic shock have been rarely reported in the immunocompromised host.
View Article and Find Full Text PDFA case of bacteremia caused by Leptotrichia trevisanii in pediatric patient with febrile neutropenia and review of literature.
Acta Microbiol Immunol Hung
May 2021
Department of Medical Microbiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Article Synopsis
- Leptotrichia species are gram-negative bacilli found in human microbiota and have become notable opportunistic pathogens, particularly in immunocompromised individuals.
- A case study identified Leptotrichia trevisanii in a five-year-old boy's central venous catheter culture, using advanced identification techniques like mass spectrometry and gene sequencing.
- Early detection of anaerobic bacteremia and timely antimicrobial treatment are crucial for preventing serious health complications in pediatric patients.
Leptotrichia trevisanii bacteremia in a woman with systemic lupus erythematosus receiving high-dose chemotherapy.
BMC Infect Dis
December 2018
Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Road 1095#, Wuhan, 430030, China.
Background: Leptotrichia species are aerotolerant, Gram-negative fusiform bacteria. Cases of bacteremia caused by Leptotrichia trevisanii in immunocompromised patients have been rarely reported.
Case Presentation: A 33-year-old female with systemic lupus erythematosus (SLE) was admitted to the department of rheumatology with bleeding from a mucosal ulcer.
Emergent genital infection by Leptotrichia trevisanii.
Infection
February 2019
Servicio de Microbiología, Instituto de Investigación Biosanitaria de Granada, Hospital Universitario Virgen de las Nieves, Avenida de las Fuerzas Armadas, 2, 18012, Granada, Spain.
We report the first case of an association between Leptotrichia trevisanii and an episode of pelvic inflammatory disease (PID) and the second case of the isolation of this infection in the cervical canal. A 45-yr-old woman was admitted to our emergency department with clinical and radiological signs and symptoms compatible with an episode of PID. She was hospitalized for intravenous antibiotic control and treatment and the subsequent surgical drainage of abscesses.
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