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| http://dx.doi.org/10.4103/1319-3767.118138 | DOI Listing |
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A Giant Nevus Lipomatosus Cutaneous Superficialis Treated With Serial Surgical Excision: A Case Report.
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Dermatology, Datta Meghe Medical College, Nagpur, IND.
Nevus lipomatosus cutaneous superficialis (NLCS) is a rare dermatological condition characterized by ectopic mature adipocytes in the dermis. The classic variety presents multiple clustered skin-colored nodules, while the solitary form is a single papule or nodule. We report the case of a 25-year-old female who presented with multiple cerebriform nodules coalescing into a large plaque over the left iliac region that developed over 17 months.
View Article and Find Full Text PDFThe Psychological Disorder and Personality Traits of Tndividuals with Pulmonary Nodules.
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December 2024
Department of Respiratory, Southeast University Affiliated Zhongda Hospital, Nanjing 210009, China. Electronic address:
Introduction: With the widespread use of Low-dose computed tomography (LDCT) in the chest, more and more people will be detected with pulmonary nodules. The presence of uncertainty following the detection of these nodules can impose significant psychological distress. This study aimed to investigate personality traits, psychological distress, and their impact on pulmonary nodule patients in China.
View Article and Find Full Text PDFRadiomics for differentiating adenocarcinoma and squamous cell carcinoma in non-small cell lung cancer beyond nodule morphology in chest CT.
Sci Rep
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Department of Radiology and Imaging Sciences, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai, 600 116, India.
Distinguishing between primary adenocarcinoma (AC) and squamous cell carcinoma (SCC) within non-small cell lung cancer (NSCLC) tumours holds significant management implications. We assessed the performance of radiomics-based models in distinguishing primary there is from SCC presenting as lung nodules on Computed Tomography (CT) scans. We studied individuals with histopathologically proven adenocarcinoma or SCC type NSCLC tumours, detected as lung nodules on Chest CT.
View Article and Find Full Text PDFAttention-based image segmentation and classification model for the preoperative risk stratification of thyroid nodules.
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Monash University Endocrine Surgery Unit, Department of General Surgery, Alfred Hospital, Melbourne, Victoria, Australia.
Background: Despite widespread use of standardized classification systems, risk stratification of thyroid nodules is nuanced and often requires diagnostic surgery. Genomic sequencing is available for this dilemma however, costs and access restricts global applicability. Artificial intelligence (AI) has the potential to overcome this issue nevertheless, the need for black-box interpretability is pertinent.
View Article and Find Full Text PDFA combined model of circulating tumor DNA methylated SHOX2/SCT/HOXA7 and clinical features facilitates the discrimination of malignant from benign pulmonary nodules.
Lung Cancer
December 2024
Department of Pathology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, China. Electronic address:
Background: Despite the advancements in early lung cancer detection attributed to the widespread use of low-dose computed tomography (LDCT), this technology has also led to an increasing number of pulmonary nodules (PNs) of indeterminate significance being identified. Therefore, this study was aimed to develop a model that leverages plasma methylation biomarkers and clinical characteristics to distinguish between malignant and benign PNs.
Methods: In a training cohort of 210 patients with PNs, we evaluated plasma circulating tumor DNA (ctDNA) for the presence of three lung cancer-specific methylation markers: SHOX2, SCT, and HOXA7.
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