Background: The aetiology behind chronic post-traumatic headache (CPTH) after mild head injury is unclear and management is complicated. In order to optimize treatment strategies we aimed to characterize a CPTH population.
Methods: Ninety patients with CPTH and 45 patients with chronic primary headaches were enrolled from the Danish Headache Center. All patients were interviewed about demographic and headache data. They completed the Harvard Trauma Questionnaire (HTQ), Rivermead Post Concussion Symptoms Questionnaire, SF-36 and a headache diary.
Results: The CPTH group experienced more cognitive ( P < 0.001) and somatic symptoms ( P = 0.048) and rated their self-perceived health as more affected in terms of physical function ( P = 0.036), physical role function ( P = 0.012) and social function ( P = 0.012) than the control group. Surprisingly, 31% of the CPTH group had a score equal to or above the cut-off score for having post-traumatic stress disorder (PTSD) according to the HTQ. In terms of demographics and headache, the groups were comparable except the CPTH group were more often without affiliation to the labour market ( P < 0.001).
Conclusions: The loss of work capacity and high levels of disability for the CPTH patients suggests directions for further research into what important factors are embedded in the patients' PTSD symptoms and might explain their prolonged illness.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1177/0333102413505236 | DOI Listing |
J Neurotrauma
January 2025
HealthPartners Institute, Bloomington, Minnesota, USA.
Connect Tissue Res
July 2023
Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada.
Background: β-Arrestin 2 (β-arr2) binds activated parathyroid hormone (PTH) receptors stimulating internalization. PTH stimulates both anabolic and catabolic effect on bone depending on the way it is administered. Intermittent PTH stimulation increases trabecular bone formation in mice, but this is decreased in mice lacking β-arr 2, suggesting a role for β-arr 2 in the anabolic effects of PTH.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2021
Key Laboratory of Applied Surface and Colloid Chemistry (Ministry of Education), School of Materials Science and Engineering, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062, P. R. China.
The modular construction of defect-free nanofilms with a large area remains a challenge. Herein, we present a scalable strategy for the preparation of calix[4]pyrrole (C[4]P)-based nanofilms through acryl hydrazone reaction conducted in a tetrahydrazide calix[4]pyrrole (CPTH)-based self-assembled layer at the air/DMSO interface. With this strategy, robust, regenerable, and defect-free nanofilms with an exceptionally large area (∼750 cm) were constructed.
View Article and Find Full Text PDFArch Oral Biol
March 2019
State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontic and Pediatric dentistry, West China Hospital of Stomatology, Sichuan University, China.
Objectives: The aim of this study was to investigate the effects of continuous parathyroid hormone (cPTH) and intermittent parathyroid hormone (iPTH) on bone formation and bone resorption in midpalatal suture during maxillary expansion.
Methods: Forty-eight male SD rats were randomly divided into four groups (n = 12 each), including the control, the expansion (E), the E + cPTH, and the E + iPTH. A thermosensitive controlled-release hydrogel was synthesized for cPTH administration.
J Headache Pain
August 2017
Head and Neck Research Group, Research Centre, Akershus University Hospital, PO Box 95, 1478, Lørenskog, Norway.
Background: Excessive daytime sleepiness (EDS, defined as Epworth sleepiness scale score > 10) is a common symptom, with a prevalence of 10-20% in the general population. It is associated with headache and other chronic pain disorders. However, little is known about the prevalence of EDS among people with secondary chronic headaches.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!