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The immune cells profiles of individuals with sulfur mustard-induced serious long-term respiratory complications.
Int Immunopharmacol
January 2025
Department of Immunology, Tarbiat Modares University, Tehran, Iran.
Sulfur mustard (SM) induced pulmonary disorder is a heterogeneous disease characterized by uncontrolled inflammatory immune responses. In this cross-sectional study carried out in Isfahan-Iran, our objective was to thoroughly evaluate the clinical health and peripheral blood leukocyte profiles of adult veterans exposed to SM 25-30 years. In total, 361 people were studied in two groups, 287 chemical veterans with pulmonary complications and 64 healthy individuals as a control group.
View Article and Find Full Text PDFHealthcare workers' knowledge and preparedness for unprecedented foodborne botulism outbreak in Saudi Arabia.
J Infect Public Health
December 2024
College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia; Evidence-Based Health Care & Knowledge Translation Research Chair, Family & Community Medicine Department, College of Medicine, King Saud University, Riyadh 11362, Saudi Arabia; Pediatric Intensive Care Unit, Pediatric Department, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia. Electronic address:
Background: The recent unprecedented foodborne botulism outbreak in Saudi Arabia necessitated an assessment of healthcare workers' (HCWs) knowledge, attitudes, and practices (KAP). This study assessed healthcare workers' knowledge regarding the transmission, contagiousness, presentation, and diagnosis of foodborne botulism, as well as their management practices, including contacting public health authorities, administering antitoxin, preparedness to respond to botulism cases and consulting generative Artificial Intelligent (AI)-chatbots, like ChatGPT.
Methods: A cross-sectional online survey targeting Saudi HCWs was conducted from May 6-19, 2024, following the first foodborne botulism outbreak.
Snake phobia among the general population of Tamil Nadu, India.
PLoS Negl Trop Dis
November 2024
School of Pharmacy, University of Reading, Reading, United Kingdom.
Article Synopsis
- The study investigates snake phobia in India, highlighting its evolutionary roots and the importance of understanding this fear in the context of preventing snakebites, which lead to significant health issues and socioeconomic impacts in the region.
- Researchers modified an existing snake phobia assessment tool (SNAQ12) and validated it in English and Tamil, collecting responses from over 2,000 individuals to analyze the prevalence and characteristics of snake phobia among the population.
- Findings indicate that males exhibit higher levels of snake phobia across all age groups compared to females in India, challenging previous assumptions that women typically experience greater phobia levels; no other significant factors were found to influence this phobia.
Snakebite-induced reversible cerebral vasoconstriction syndrome: Report of three cases.
Toxicon
November 2024
School of Pharmacy, University of Reading, Reading, RG6 6UB, UK. Electronic address:
Envenomings from Russell's viper typically result in local tissue damage and bleeding complications, but the bites from common krait and cobra primarily cause neurotoxic effects. While most symptoms can be treated with appropriate antivenom, additional support is necessary for several snakebite victims to tackle a broad range of unusual complications that they develop following bites. Reversible vasoconstriction syndrome (RCVS), characterised by the constriction of cerebral arteries, is a rare but serious issue, presenting with severe headaches and, in extreme cases, haemorrhagic/ischaemic stroke.
View Article and Find Full Text PDFImproved Localization of Insulinomas Using Ga-NODAGA-Exendin-4 PET/CT.
J Nucl Med
December 2024
Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.
Article Synopsis
- The study compares the effectiveness of Ga-NODAGA-exendin-4 PET/CT to traditional imaging methods for locating insulinomas, a type of tumor that causes low blood sugar.
- Exendin PET/CT showed a significantly higher diagnostic accuracy (94.4%) compared to DOTA-SSA PET/CT (64.8%), CT/MRI (83.3%), and endoscopic ultrasound (82.8%).
- The findings suggest that exendin PET/CT offers better image quality and consistency among observers, making it a valuable tool for the preoperative assessment of insulinomas.
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