Coupling biocatalysis with molecular imprinting in a biomimetic sensor.

Angew Chem Int Ed Engl

Fraunhofer Institute for Biomedical Engineering, Am Mühlenberg 13, 14476 Potsdam (Germany); Institute of Biochemistry and Biology, University of Potsdam, Karl-Liebknecht-Strasse 24-25, 14476 Potsdam (Germany).

Published: October 2013

Make it simple: A molecularly imprinted electropolymer was combined with an enzyme in a catalytic biomimetic sensor that enabled interference-free detection of the drug aminopyrine (AP) at submicromolar concentrations in the presence of ascorbic acid and uric acid within 15 s. The sensor functioned by the peroxide-dependent conversion of AP in a layer above a product-imprinted electropolymer on an indicator electrode.

Download full-text PDF

Source
http://dx.doi.org/10.1002/anie.201305368DOI Listing

Publication Analysis

Top Keywords

biomimetic sensor
8
coupling biocatalysis
4
biocatalysis molecular
4
molecular imprinting
4
imprinting biomimetic
4
sensor simple
4
simple molecularly
4
molecularly imprinted
4
imprinted electropolymer
4
electropolymer combined
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!