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Peripheral Ameloblastoma Resembling an Exophytic Gingival Lesion: A Report of a Rare Case.
Cureus
November 2024
Oral and Maxillofacial Surgery, Burdwan Dental College and Hospital, Burdwan, IND.
Peripheral ameloblastoma is a rare, benign, slow-growing odontogenic neoplasm prevalent in the mandible. It originates from the odontogenic epithelium and its remnants, and its histological characteristics are identical to those of intraosseous ameloblastoma. It is less aggressive and invasive than its intraosseous variety, with a low recurrence rate.
View Article and Find Full Text PDFGenomic and transcriptomic analysis of ameloblastoma reveals distinct molecularly aggressive phenotypes.
Mod Pathol
December 2024
Liverpool Head and Neck Centre, Molecular and Clinical Cancer Medicine, University of Liverpool, 6 West Derby Street, Liverpool, L6 8TX. Electronic address:
Ameloblastoma (AM) is a benign but locally infiltrative epithelial odontogenic neoplasm of the jawbones that may reach grotesque proportions and be highly recurrent if inadequately removed. The BRAF mutation has been demonstrated as key molecular event in its development, nevertheless, there are many queries about its aetiopathogenesis that are yet to be answered. In this study, we aimed to integrate results from whole-exome sequencing (WES) and RNA-sequencing in AM samples to identify novel candidate genes that may be relevant to its pathogenesis.
View Article and Find Full Text PDFEnhancing Precision and Esthetics: Endoscopy-Assisted Total Maxillectomy for Locally Invasive Maxillary Ameloblastoma Using Contralateral Transmaxillary Approach Without Subciliary Incision.
Cureus
November 2024
Otolaryngology and Head and Neck Surgery, Kobe City Medical Center General Hospital, Kobe, JPN.
This report presents a notable approach to treating a locally invasive maxillary ameloblastoma in a 46-year-old woman using an endoscopy-assisted total maxillectomy via a contralateral transmaxillary approach without a subciliary incision. Ameloblastomas, though benign, require radical surgical management due to their aggressive nature and high recurrence rates, especially in the maxilla. Traditional techniques often involve extensive facial incisions, leading to significant scarring and potential complications.
View Article and Find Full Text PDFDesmoplastic Ameloblastoma: A case report of rare pulmonary metastasis.
Heliyon
December 2024
Department of Oral and Maxillofacial Surgery, Showa University School of Dentistry, Tokyo 145-8515, Japan.
Pulmonary metastasis of ameloblastoma is a rare associated with the histopathologically plexiform types of ameloblastoma. In this report, we present an exceptionally rare case of pulmonary metastatic ameloblastoma without local recurrence, emerging 12 years post-initial resection. A female patient, initially diagnosed with mandibular desmoplastic ameloblastoma, revealed masses in both lung fields of the lung on chest radiography, while chest computed tomography revealed more than 10 nodules in both lungs.
View Article and Find Full Text PDFAnalysis of recurrence factors after radical mandibular resection for ameloblastoma.
J Stomatol Oral Maxillofac Surg
December 2024
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, 430079, Wuhan, PR China; Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, 430079, Wuhan, PR China. Electronic address:
Background: To analyze causes of recurrence following radical mandibular resection of ameloblastoma, and to propose surgical variation.
Methods: We conducted a retrospective analysis of patients treated for ameloblastoma from 2012 to 2024, specifically those who underwent radical mandibular resection followed by reconstruction with autologous bone flaps, focusing on cases of recurrence.
Results: Six patients were included in the study, all with primary tumors located in the mandible.
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