Guillain-Barre syndrome with acute lymphoblastic leukemia.

Indian Pediatr

Division of Pediatric Oncology, Regional Cancer Centre; and *Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, India. Correspondence to: Dr Binitha Rajeswari, Lecturer, Division of Pediatric Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala 695 011, India.

Published: August 2013

Guillain-Barre syndrome (GBS) is rarely reported in children with acute lymphoblastic leukemia and may be difficult to differentiate from vincristine induced neuropathy. We report two children with acute lymphoblastic leukemia on induction chemotherapy who developed GBS. The diagnostic issues and potential pathogenic mechanisms underlying GBS in pediatric patients with ALL are discussed.

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Source
http://dx.doi.org/10.1007/s13312-013-0201-2DOI Listing

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