Recent studies have experienced the acceleration of convergence in Markov chain Monte Carlo methods implemented by the systems without detailed balance condition (DBC). However, such advantage of the violation of DBC has not been confirmed in general. We investigate the effect of the absence of DBC on the convergence toward equilibrium. Surprisingly, it is shown that the DBC violation always makes the relaxation faster. Our result implies the existence of a kind of thermodynamic inequality that connects the nonequilibrium process relaxing toward steady state with the relaxation process which has the same probability distribution as its equilibrium state.
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http://dx.doi.org/10.1103/PhysRevE.88.020101 | DOI Listing |
BMC Genomics
January 2025
Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.
Background: The burden of Clostridioides difficile as a nosocomial- and community-acquired pathogen has been increasing over the recent decades, including reports of severe outbreaks. Molecular and virulence genotyping are central for the epidemiological surveillance of this pathogen, but need to balance accuracy and rapid turnaround time of the results. While Illumina short-read sequencing has been adopted as the gold standard to investigate C.
View Article and Find Full Text PDFJDS Commun
January 2025
Animal and Dairy Sciences Department, University of Wisconsin-Madison, Madison, WI 53706.
In the face of diminishing economic margins, dairy farmers globally are compelled to maintain economic competitiveness. Benchmarking emerges as a strategic tool to establish new, achievable improvement objectives that balance ambition with practicality. This typically requires integrating diverse data sources, such as feed, milk production, diet, and market prices.
View Article and Find Full Text PDFOptical information synthesis, which fuses LiDAR and optical cameras, has the potential for highly detailed 3D representations. However, due to the disparity of information density between point clouds and images, conventional matching methods based on points often lose significant information. To address this issue, we propose a regional matching method to bridge the differences in information density between point clouds and images.
View Article and Find Full Text PDFPilot Feasibility Stud
January 2025
University of Ottawa Heart Institute, Ottawa, Canada.
Background: Cigarette smoking is a leading cause of death and disease, including those related to the cardiovascular system. Cytisine is a plant-based medication, which works in a similar mechanism to varenicline. It is safe, efficacious, and cost-effective for smoking cessation.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Geography and Spatial Sciences, University of Delaware, Newark, DE, USA.
Water is crucial for meeting sustainability targets, but its unsustainable use threatens human wellbeing and the environment. Past assessments of water scarcity (i.e.
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