This study was concerned with the problem how we should allow for gestational age at birth when evaluating psychomotor development in extremely low birthweight (ELBW) infants. The consequences of the use of corrected and uncorrected developmental test scores as to the degree of prematurity were studied in 27 consecutive ELBW children who had been categorized as being normal on neurological and psychological testing at 5 1/2 years. The present study provides evidence that the overall trend of psychomotor development in normal ELBW children is not accelerated, but is guided by maturation of the central nervous system. This study also suggests that there are no significant differences in the predictive value of corrected and uncorrected DQ scores after 2 years of age with respect to IQ scores at 5 1/2 years.
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http://dx.doi.org/10.1016/s0387-7604(12)80316-0 | DOI Listing |
Eur Thyroid J
January 2025
H Heuer, Department of Endocrinology, Diabetes and Metabolism, University of Duisburg-Essen, Essen, Germany.
Objective: Mutations in the thyroid hormone (TH) transporter monocarboxylate transporter 8 (MCT8) cause Allan-Herndon-Dudley syndrome (AHDS), a severe form of psychomotor retardation with muscle hypoplasia and spastic paraplegia as key symptoms. These abnormalities have been attributed to an impaired TH transport across brain barriers and into neural cells thereby affecting brain development and function. Likewise, Mct8/Oatp1c1 (organic anion transporting polypeptide 1c1) double knockout (M/Odko) mice, a well-established murine AHDS model, display a strongly reduced TH passage into the brain as well as locomotor abnormalities.
View Article and Find Full Text PDFRecent calls for Doctor of Physical Therapy (DPT) education to cultivate the affective domain or "habits of the heart" have highlighted a gap in curricula, where cognitive and psychomotor learning domains are often the focus. Balint groups, traditionally used in medical education, offer a potential method for addressing this gap. These small peer discussion groups provide a space for students to reflect on the emotional and interpersonal complexities of providing patient care through practicing perspective-taking.
View Article and Find Full Text PDFJMIR Form Res
January 2025
School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Background: Origami is a popular activity among preschool children and can be used by therapists as an evaluation tool to assess children's development in clinical settings. It is easy to implement, appealing to children, and time-efficient, requiring only simple materials-pieces of paper. Furthermore, the products of origami may reflect children's ages and their visual-motor integration (VMI) development.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), S.A.S. Nagar, Punjab, India.
Neuropathic pain, a challenging condition often associated with diabetes, trauma, or chemotherapy, impairs patients' quality of life. Current treatments often provide inconsistent relief and notable adverse effects, highlighting the urgent need for safer and more effective alternatives. This review investigates marine-derived bioactive compounds as potential novel therapies for neuropathic pain management.
View Article and Find Full Text PDFEur J Dent Educ
January 2025
Faculty of Medicine and Dentistry, School of Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Introduction: Evidence on the pre-clinical and clinical performance of internationally trained dental students compared with domestic students and competency standards is limited. The aim of this study was to compare, relatively and normatively, the psychomotor skills of domestic and internationally trained dental students who participated in the same pre-clinical, 9-week, fixed prosthodontics course.
Materials And Methods: Course grades were collected for a total of 224 domestic and 66 internationally trained dental students between 2014 and 2020.
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