Intrasinus thrombolysis by mechanical and urokinase for severe cerebral venous sinus thrombosis : a case report.

Purpose: Cerebral venous and sinus thrombosis (CVST) is a rare stroke disorder, which requires prompt recognition and appropriate intervention to prevent a devastating outcome. Intrasinus thrombolysis is an alternative and effective method to anticoagulant therapy for the treatment of CVST, but is rarely used in Taiwan.

Case Report: A 46-year-old man presented with a one-week history of intractable headache and progressive weakness of his right lower limb. Magnetic resonance venography of the brain confirmed a diagnosis of extensive venous sinus thrombosis. The patient was successfully treated by direct intrasinus thrombolysis with urokinase.

Conclusion: This case highlights the benefit of early intrasinus thrombolysis for the treatment of CVST.