AI Article Synopsis
- CLA may have long-term side effects and its effectiveness in humans is debated, prompting interest in alternative biomolecules like conjugated linolenic acid (CLNA).
- CLNA shows promise as an anti-obesity molecule and may offer additional benefits beyond weight loss, but requires higher doses than CLA for effectiveness.
- Limited research on CLNA means that more studies are needed to understand its potential impact on obesity-related issues such as insulin resistance, dyslipidemia, and inflammation.
Article Abstract
Despite its benefits, conjugated linoleic acid (CLA) may cause side effects after long-term administration. Because of this and the controversial efficacy of CLA in humans, alternative biomolecules that may be used as functional ingredients have been studied in recent years. Thus, conjugated linolenic acid (CLNA) has been reported to be a potential anti-obesity molecule which may have additional positive effects related to obesity. According to the results reported in obesity, CLNA needs to be given at higher doses than CLA to be effective. However, because of the few studies conducted so far, it is still difficult to reach clear conclusions about the potential use of these CLNAs in obesity and its related changes (insulin resistance, dyslipidemia, or inflammation).
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| http://dx.doi.org/10.1016/j.endonu.2013.04.016 | DOI Listing |
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