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Utility of hybrid whole genome sequencing in assessing potential nosocomial VIM transmission.
Antimicrob Steward Healthc Epidemiol
August 2024
Department of Community Health and Epidemiology, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada.
Hybrid whole genome sequencing was used to investigate if nosocomial Verona integron-encoded metallo-β-lactamase (VIM) carbapenemase transmission occurred between two patients without epidemiological links or common pathogens. Challenges in genomic methodology and appropriate analytical depth for mobile carbapenemase outbreaks are described including how inappropriate choices can mislead results and impact infection control practices.
View Article and Find Full Text PDFOptimized nursing management in the Central Sterile Supply Department and Gastroenterology Department: a retrospective controlled study.
Am J Transl Res
December 2024
Endoscopy Center of Gastroenterology Department, General Hospital of Central Theater Command Wuhan 430070, Hubei, China.
Objective: To evaluate the impact of optimized nursing management involving the Central Sterile Supply Department (CSSD) and Gastroenterology Department on sterilization processes, nurse well-being, and patient satisfaction.
Methods: This retrospective study analyzed data from 40 CSSD nurses and sterilization metrics for 1,017 gastroenterology instruments before and after implementing optimized management. The study included a control group (CG) prior to the intervention and an experimental group (EG) after.
Path analysis of factors influencing registered nurses' safety behavior in China: A mediation effect model.
Jpn J Nurs Sci
January 2025
Department of Rehabilitation Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Objective: This study aims to examine the current state, influencing factors, and pathways of safety behavior among registered nurses in China, thereby providing a theoretical framework for enhancing safety behavior levels among registered nurses.
Methods: The research involved the recruitment of registered nurses in Chongqing, China, utilizing the snowball sampling technique from July 2022 to May 2023.
Results: A total of 3244 registered nurses from 115 hospitals in Chongqing participated in the study.
The contribution of community transmission to the burden of hospital-associated pathogens: A systematic scoping review of epidemiological models.
One Health
June 2025
One Health Trust, Washington DC, USA.
Healthcare-associated infections (HAI), particularly those involving multi-drug resistant organisms (MDRO), pose a significant public health threat. Understanding the transmission of these pathogens in short-term acute care hospitals (STACH) is crucial for effective control. Mathematical and computational models play a key role in studying transmission but often overlook the influence of long-term care facilities (LTCFs) and the broader community on transmission.
View Article and Find Full Text PDFComparison of antimicrobial efficacy and therapeutic index properties for common wound cleansing solutions, focusing on solutions containing PHMB.
GMS Hyg Infect Control
December 2024
5D Health Protection Group Ltd, Liverpool, UK.
Background: Surgical site infections (SSIs) have been shown to increase patient morbidity and mortality, impact on quality of life and place a significant economic burden on healthcare systems worldwide. Irrigation using wound cleansing and antiseptic effective solutions during surgical procedures is a key part of SSI prevention. The optimal solution would have minimal cytotoxicity to the patient while maintaining a minimum concentration required for antimicrobial activity necessary to prevent opportunistic pathogens and biofilm formation.
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