AI Article Synopsis
- Researchers screened 1,750 pneumococcal isolates using PCR to identify common serotypes, then analyzed those that were PCR-negative with the Quellung reaction.
- The results from PCR matched the Quellung reaction for 99% of the isolates tested.
- The combination of PCR followed by Quellung is not only accurate but also more cost-effective than using the Quellung reaction alone.
Article Abstract
Screening of 1,750 pneumococcal isolates for common serotypes by PCR was followed by Quellung reaction analysis of PCR-negative isolates with a comparison to the conventional (Quellung reaction only) approach. PCR agreed with Quellung reaction results for 99% of isolates. The sequential PCR/Quellung reaction algorithm is accurate and more cost-effective than the conventional approach.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838036 | PMC |
| http://dx.doi.org/10.1128/JCM.01876-13 | DOI Listing |
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