AI Article Synopsis
- This study presents a method using Magic Tag® to immobilize bioactive molecules and bacteriophage display to analyze drug interactions.
- The focus is on how flecainide, a drug, binds to proteins related to genes associated with sudden cardiac death.
- An ELISA assay is used as part of the protocol to probe these interactions effectively.
Article Abstract
Magic Tag® immobilisation of bioactive molecules coupled with bacteriophage display, followed by an ELISA assay, provides a protocol that can probe interactions of drugs with putative products of alternative initiation of translation as exemplified by the binding of immobilised flecainide to protein products of genes linked to sudden cardiac death.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c3cc44647f | DOI Listing |
Publication Analysis
Top Keywords
bioactive molecules
8
chemical genomics
4
genomics approach
4
approach identification
4
identification interactions
4
interactions bioactive
4
molecules alternative
4
alternative reading
4
reading frame
4
frame proteins
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!