Tapentadol is a novel, centrally acting analgesic with dual mechanism of action, combining mu-opioid receptor agonism with noradrenaline reuptake inhibition in the same molecule. It has an improved side effect profile when compared to opioids and nonsteroidal anti-inflammatory drugs. The dual mechanism of action makes Tapentadol a useful analgesic to treat acute, chronic, and neuropathic pain.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757808 | PMC |
| http://dx.doi.org/10.4103/1658-354X.115319 | DOI Listing |
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